Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury

Chang-Hong Du; Yi-Ding Wu; Ke Yang; Wei-Nian Liao; Li Ran; Chao-Nan Liu; Shu-Zhen Zhang; Kuan Yu; Jun Chen; Yong Quan; Mo Chen; Ming-Qiang Shen; Hong Tang; Shi-Lei Chen; Song Wang; Jing-Hong Zhao; Tian-Min Cheng; Jun-Ping Wang

doi:10.1186/s40779-023-00499-z

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Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury

RESEARCH | Updated：2025-12-13

- Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury
- Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury
- “一项新的研究介绍了其在血小板减少症领域的研究进展。专家们建立了放射性损伤诱导的血小板减少症的小鼠模型，并探索了潜在的致病机制，为解决血栓形成问题提供了解决方案。”
- MMR 2024年11卷第6期页码：797-817
- Affiliations：
  
  1.State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Combined Injury, Chongqing Engineering Research Center for Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing 400038, China
  2.Frontier Medical Training Brigade, Army Medical University, Hutubi 831200, Xinjiang, China
  3.Department of Nephrology, the Key Laboratory for the Prevention and Treatment of Chronic Kidney Disease of Chongqing, Kidney Center of PLA, Xinqiao Hospital, Army Medical University, Chongqing 400037, China
- Author bio：
  
  *changhongdu@tmmu.edu.cn;
  wangjunping@tmmu.edu.cn
- Funds：
  
  the Key Program of the National Natural Science Foundation of China(81930090);the National Science Foundation for Distinguished Young Scholars of China(81725019);the National Natural Science Foundation of China(32171104;82273571;81874256);the Chongqing Natural Science Foundation(2023NSCQ-MSX0687;CSTB2023NSCQ-JQX0015;cstc2015jcyjys10001);the Chongqing Talent Program(CQYC20220511002)
- DOI：10.1186/s40779-023-00499-z
  中图分类号：
- 纸质出版：2024-12
- Accepted：
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Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury[J]. MMR, 2024,11(6):797-817.

Cite this article as: Du CH, Wu YD, Yang K, Liao WN, Ran L, Liu CN, et al. Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury. Mil Med Res. 2023;10(1):66.
Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury[J]. MMR, 2024,11(6):797-817. DOI： 10.1186/s40779-023-00499-z.

Cite this article as: Du CH, Wu YD, Yang K, Liao WN, Ran L, Liu CN, et al. Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury. Mil Med Res. 2023;10(1):66. DOI： 10.1186/s40779-023-00499-z.

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Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury

Apoptosis-resistant megakaryocytes produce large and hyperreactive platelets in response to radiation injury

DOI：10.1186/s40779-023-00499-z