BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition

Yu Meng; Hui-Yan Sun; Yi He; Qian Zhou; Yi-Huang Liu; Hui Su; Ming-Zhu Yin; Fu-Rong Zeng; Xiang Chen; Guang-Tong Deng

doi:10.1186/s40779-023-00497-1

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BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition

LETTER TO THE EDITOR | Updated：2025-12-13

- BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition
- BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition
- “在xxx领域，xx专家取得了重大的研究进展。通过建立xx体系/探索xx主题/验证xx猜想，他们为解决xx问题提供了解决方案/为xx研究开辟了新方向/为xx体系的构建奠定了基础。”
- MMR 2024年11卷第4期页码：620-624
- Affiliations：
  
  1.Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008, China
  2.National Engineering Research Center of Personalized Diagnostic and Therapeutic Technology, Changsha 410008, China
  3.Furong Laboratory, Changsha 410008, China
  4.Hunan Key Laboratory of Skin Cancer and Psoriasis, Hunan Engineering Research Center of Skin Health and Disease, Xiangya Hospital, Central South University, Changsha 410008, China
  5.National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha 410008, China
  6.Department of Breast Reconstruction, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300202, China
  7.Department of Oncology, Xiangya Hospital, Central South University, Changsha 410008, China
- Author bio：
  
  Yu Meng, Hui-Yan Sun and Yi He contributed equally to this work
  *zengflorachn@hotmail.com;
  chenxiangck@126.com;
  dengguangtong@outlook.com
- Funds：
  
  the National Natural Science Foundation of China(82103183;82102803;82272849);the Natural Science Foundation of Hunan Province(2022JJ40767;2021JJ40976);the Natural Science Fund for Outstanding Youths in Hunan Province(2023JJ20093);the National Key Research and Development Program(2022YFC2504700)
- DOI：10.1186/s40779-023-00497-1
  中图分类号：
- 纸质出版：2024-08
- Accepted：
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BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition[J]. MMR, 2024,11(4):620-624.

Cite this article as: Meng Y, Sun HY, He Y, Zhou Q, Liu YH, Su H, et al. BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition. Mil Med Res. 2023;10(1):61.
BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition[J]. MMR, 2024,11(4):620-624. DOI： 10.1186/s40779-023-00497-1.

Cite this article as: Meng Y, Sun HY, He Y, Zhou Q, Liu YH, Su H, et al. BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition. Mil Med Res. 2023;10(1):61. DOI： 10.1186/s40779-023-00497-1.

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BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition

BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition

DOI：10.1186/s40779-023-00497-1