Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges

Jia-Yi Ding; Min-Jiang Chen; Ling-Feng Wu; Gao-Feng Shu; Shi-Ji Fang; Zhao-Yu Li; Xu-Ran Chu; Xiao-Kun Li; Zhou-Guang Wang; Jian-Song Ji

doi:10.1186/s40779-023-00472-w

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Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges

REVIEW | Updated：2025-12-13

- Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges
- Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges
- “报告了伤口修复的最新进展，全面概述了间充质干细胞衍生的细胞外囊泡在促进皮肤伤口愈合方面的巨大潜力。专家研究已经确定了这些囊泡的治疗应用，它们可以再生血管、神经和毛囊，抑制瘢痕形成，并作为伤口修复组件的支架。这一探索为伤口修复临床治疗体系的构建奠定了基础。”
- MMR 2024年11卷第3期页码：400-429
- Affiliations：
  
  1.Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Institute of Imaging Diagnosis and Minimally Invasive Intervention Research, the Fifth Affiliated Hospital of Wenzhou Medical University, Zhejiang, Lishui 323000, China
  2.Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China
  3.Clinical College of the Affiliated Central Hospital, School of Medicine, Lishui University, Lishui 323000, Zhejiang, China
  4.Department of Overseas Education College, Jimei University, Xiamen 361021, Fujian, China
  5.Department of Medicine II, Internal Medicine, Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, 35392 Giessen, Germany
  6.Pulmonary and Critical Care, Department of Medicine V, Internal Medicine, Infectious Diseases and Infection Control, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, 35392 Giessen, Germany
- Author bio：
  
  *xiaokunli@wmu.edu.cn; lixk1964@163.com;
  wangzhouguang@wmu.edu.cn; wzhouguang@gmail.com;
  jijiansong@zju.edu.cn
- Funds：
  
  the National Key Research and Development Project Intergovernmental Cooperation in Science and Technology of China(2018YFE0126900);the Key R&D Program of Lishui City(2021ZDYF12);the National Natural Science Foundation of China(82271629)
- DOI：10.1186/s40779-023-00472-w
  中图分类号：
- 纸质出版：2024-06
- Accepted：
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Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges[J]. MMR, 2024,11(3):400-429.

Cite this article as: Ding JY, Chen MJ, Wu LF, Shu GF, Fang SJ, Li ZY, et al. Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges. Mil Med Res. 2023;10(1):36.
Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges[J]. MMR, 2024,11(3):400-429. DOI： 10.1186/s40779-023-00472-w.

Cite this article as: Ding JY, Chen MJ, Wu LF, Shu GF, Fang SJ, Li ZY, et al. Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges. Mil Med Res. 2023;10(1):36. DOI： 10.1186/s40779-023-00472-w.

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Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges

Mesenchymal stem cell-derived extracellular vesicles in skin wound healing: roles, opportunities and challenges

DOI：10.1186/s40779-023-00472-w