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The marriage of immunomodulatory, angiogenic, and osteogenic capabilities in a piezoelectric hydrogel tissue engineering scafold for military medicine
RESEARCH | Updated：2025-12-13

    • The marriage of immunomodulatory, angiogenic, and osteogenic capabilities in a piezoelectric hydrogel tissue engineering scafold for military medicine

    • The marriage of immunomodulatory, angiogenic, and osteogenic capabilities in a piezoelectric hydrogel tissue engineering scafold for military medicine

    • “在骨组织工程领域，研究人员开发了一种促进骨再生的压电水凝胶骨支架。该团队将PDA修饰的陶瓷羟基磷灰石和PDA修饰的钛酸钡纳米粒子掺入壳聚糖/明胶基质中，增强了支架的机械性能和自发电。压电水凝胶在免疫调节、血管生成和成骨方面表现出细胞相容性和能力，有效地诱导巨噬细胞极化为M2表型，促进人脐静脉内皮细胞的迁移、管形成和血管生成分化，并促进MC3T3-E1细胞的移行、骨分化和细胞外基质矿化。体内评估表明，这些水凝胶显著促进了大鼠大型颅脑损伤模型中新骨的形成，为提高基层部队的战斗力提供了一种新策略。”
    • MMR   2024年11卷第3期 页码：323-344

    • DOI：10.1186/s40779-023-00469-5    

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    • 纸质出版：2024-06

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  • The marriage of immunomodulatory, angiogenic, and osteogenic capabilities in a piezoelectric hydrogel tissue engineering scafold for military medicine[J]. MMR, 2024,11(3):323-344. DOI： 10.1186/s40779-023-00469-5.

    Cite this article as: Wu P, Shen L, Liu HF, Zou XH, Zhao J, Huang Y, et al. The marriage of immunomodulatory, angiogenic, and osteogenic capabilities in a piezoelectric hydrogel tissue engineering scafold for military medicine. Mil Med Res. 2023;10(1):35. DOI： 10.1186/s40779-023-00469-5.

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