Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases

Qian Li; Chun Dang; Li-Hua Wang

doi:10.1186/s40779-022-00431-x

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Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases

COMMENTARY | Updated：2023-09-05

- Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases
- Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases
- MMR 2023年10卷第4期页码：556-558
- Affiliations：
  
  1.Department of Neurology, the Second Affiliated Hospital of Harbin Medical University, Harbin 150081, China
  2.Department of Periodical Press, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610000, China
- Author bio：
  
  * drliqian@hrbmu.edu.cn;
  wanglh211@163.com
- Funds：
  
  grants from the National Natural Science Foundation of China(82001240);the Natural Science Foundation of Heilongjiang Province(YQ2021H011);the China Postdoctoral Science Foundation(2020M670925;2022T150172);the Postdoctoral Foundation of Heilongjiang Province(LBHZ19027;LBH-TZ2019)
- DOI：10.1186/s40779-022-00431-x
  中图分类号：
- 纸质出版：2023-08
- Accepted：
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Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases[J]. MMR, 2023,10(4):556-558.

Li Q, Dang C, Wang LH. Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases. Mil Med Res. 2022;9(1):72.
Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases[J]. MMR, 2023,10(4):556-558. DOI： 10.1186/s40779-022-00431-x.

Li Q, Dang C, Wang LH. Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases. Mil Med Res. 2022;9(1):72. DOI： 10.1186/s40779-022-00431-x.

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Hampshire A , Trender W , Chamberlain SR , Jolly AE , Grant JE , Patrick F , et al . Cognitive deficits in people who have recovered from COVID-19 . EClinicalMedicine . 2021 ; 39 : 101044 .

Crook H , Raza S , Nowell J , Young M , Edison P . Long covid—mechanisms, risk factors, and management . BMJ . 2021 ; 374 : n1648 .

Fernández-Castañeda A , Lu P , Geraghty AC , Song E , Lee MH , Wood J , et al . Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation . Cell . 2022 ; 185 ( 14 ): 2452 - 68 .

Hosang L , Canals RC , van der Flier FJ , Hollensteiner J , Daniel R , Flügel A , et al . The lung microbiome regulates brain autoimmunity . Nature . 2022 ; 603 ( 7899 ): 138 - 44 .

Gorelick PB . Role of inflammation in cognitive impairment: results of observational epidemiological studies and clinical trials . Ann N Y Acad Sci . 2010 ; 1207 ( 1 ): 155 - 62 .

Mehta P , Mcauley DF , Brown M , Sanchez E , Tattersall RS , Manson JJ . COVID-19: consider cytokine storm syndromes and immunosuppression . Lancet . 2020 ; 395 ( 10229 ): 1033 - 4 .

Wan D , Du T , Hong W , Chen L , Que H , Lu S , et al . Neurological complications and infection mechanism of SARS-COV-2 . Signal Transduct Target Ther . 2021 ; 6 ( 1 ): 406 .

Taquet M , Sillett R , Zhu L , Mendel J , Camplisson I , Dercon Q , et al . Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients . Lancet Psychiatry . 2022 ; 9 ( 10 ): 815 - 27 .

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