Advances in electrical impedance tomography-based brain imaging

Xi-Yang Ke; Wei Hou; Qi Huang; Xue Hou; Xue-Ying Bao; Wei-Xuan Kong; Cheng-Xiang Li; Yu-Qi Qiu; Si-Yi Hu; Li-Hua Dong

doi:10.1186/s40779-022-00370-7

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Advances in electrical impedance tomography-based brain imaging

REVIEW | Updated：2023-03-20

- Advances in electrical impedance tomography-based brain imaging
- Advances in electrical impedance tomography-based brain imaging
- 解放军医学杂志（英文版） 2022年9卷第6期页码：705-726
- Affiliations：
  
  1.Department of Radiation Oncology and Therapy, the First Hospital of Jilin University, Changchun 130021, China
  2.Jilin Provincial Key Laboratory of Radiation Oncology and Therapy, the First Hospital of Jilin University, Changchun 130021, China
  3.NHC Key Laboratory of Radiobiology, School of Public Health, Jilin University, Changchun 130021, China
  4.CAS Key Laboratory of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, Jiangsu, China
- Author bio：
  
  * husiyi@sibet.ac.cn;
  dlh@jlu.edu.cn
- Funds：
  
  the National Natural Science Foundation of China(81773353);Jilin Scientific and Technological Development Program(20200404148YY;20200601005JC;20210101317JC);Jilin Province Special Project of Medical and Health Talents(JLSCZD2019-032);the Research Funding Program of Norman Bethune Biomedical Engineering Center(BQEGCZX2019025);National College Students Innovation and Entrepreneurship Training Program (CN)(202010183691)
- DOI：10.1186/s40779-022-00370-7
  中图分类号：
- 纸质出版：2022-12
- Accepted：
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Advances in electrical impedance tomography-based brain imaging[J]. 解放军医学杂志（英文版）, 2022,9(6):705-726.

Ke XY, Hou W, Huang Q, Hou X, Bao XY, Kong WX, et al. Advances in electrical impedance tomography-based brain imaging. Mil Med Res. 2022;9(1):10.
Advances in electrical impedance tomography-based brain imaging[J]. 解放军医学杂志（英文版）, 2022,9(6):705-726. DOI： 10.1186/s40779-022-00370-7.

Ke XY, Hou W, Huang Q, Hou X, Bao XY, Kong WX, et al. Advances in electrical impedance tomography-based brain imaging. Mil Med Res. 2022;9(1):10. DOI： 10.1186/s40779-022-00370-7.

摘要

Abstract

Novel advances in the field of brain imaging have enabled the unprecedented clinical application of various imaging modalities to facilitate disease diagnosis and treatment. Electrical impedance tomography (EIT) is a functional imaging technique that measures the transfer impedances between electrodes on the body surface to estimate the spatial distribution of electrical properties of tissues. EIT offers many advantages over other neuroimaging technologies

which has led to its potential clinical use. This qualitative review provides an overview of the basic principles

algorithms

and system composition of EIT. Recent advances in the field of EIT are discussed in the context of epilepsy

stroke

brain injuries and edema

and other brain diseases. Further

we summarize factors limiting the development of brain EIT and highlight prospects for the field. In epilepsy imaging

there have been advances in EIT imaging depth

from cortical to subcortical regions. In stroke research

a bedside EIT stroke monitoring system has been developed for clinical practice

and data support the role of EIT in multi-modal imaging for diagnosing stroke. Additionally

EIT has been applied to monitor the changes in brain water content associated with cerebral edema

enabling the early identification of brain edema and the evaluation of mannitol dehydration. However

anatomically realistic geometry

inhomogeneity

cranium completeness

anisotropy and skull type

etc.

must be considered to improve the accuracy of EIT modeling. Thus

the further establishment of EIT as a mature and routine diagnostic technique will necessitate the accumulation of more supporting evidence.

关键词

Keywords

references

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