Early stage nonclinical pulmonary disorder in COVID-19 may present asymptomatic and fuel the contagion[J]. 解放军医学杂志(英文版), 2021,8(4):584-586.
Adedokun: Early stage nonclinical pulmonary disorder in COVID-19 may present asymptomatic and fuel the contagion. Mil Med Res,2021, 8: 22.
Early stage nonclinical pulmonary disorder in COVID-19 may present asymptomatic and fuel the contagion[J]. 解放军医学杂志(英文版), 2021,8(4):584-586. DOI: 10.1186/s40779-021-00316-5.
Adedokun: Early stage nonclinical pulmonary disorder in COVID-19 may present asymptomatic and fuel the contagion. Mil Med Res,2021, 8: 22. DOI: 10.1186/s40779-021-00316-5.
Early stage nonclinical pulmonary disorder in COVID-19 may present asymptomatic and fuel the contagion
Evidence shows that pulmonary problems in coronavirus disease 2019 (COVID-19) may set off from vascular injury that progresses to physiological disturbances through a compromised gas exchange
following an infection with the severe acute respiratory syndrome coronavirus 2. In this process
inefficient gas exchange in the alveolar could precipitate silent nonclinical hypoxemia. Unfortunately
patients with "silent hypoxemia" do not necessarily experience any breathing difficulty (dyspnea) at the early stage of COVID-19 while the disease progresses. As a result
several asymptomatic
presymptomatic and patients with mild symptoms may escape quarantine measure and thus continue to spread the virus through contacts. Therefore
early diagnosis of "silent hypoxemia "
which attracts no clinical warnings
could be an important diagnostic measure to prevent acute respiratory distress syndrome from the risk of pulmonary failure among the presymptomatic and as a screening tool in the asymptomatic who are hitherto potential spreaders of the virus.
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Shah S , Majmudar K , Stein A , Gupta N , Suppes S , Karamanis M , et al . Novel use of home pulse oximetry monitoring in COVID-19 patients discharged from the emergency department identifies need for hospitalization . Acad Emerg Med . 2020 ; 27 ( 8 ): 681 - 92 . https://doi.org/10.1111/acem.14053 https://doi.org/10.1111/acem.14053 .
Gopalakrishnan S , Karmani S , Pandey A , Singh A , Kumar JR , Praveen R , et al . Pulse oximetry screening to detect critical congenital heart diseases in asymptomatic neonates . Med J Armed Forces India . 2020; https://doi.org/10.1016/j.mjafi.2020.09.004 https://doi.org/10.1016/j.mjafi.2020.09.004 .
Bickler PE , Feiner JR , Lipnick MS , McKleroy W . “silent” presentation of hypoxemia and cardiorespiratory compensation in COVID-19 . Anesthesiology . 2021 ; 134 ( 2 ): 262 - 9 . https://doi.org/10.1097/ALN.0000000000003578 https://doi.org/10.1097/ALN.0000000000003578 .
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相关作者
Dai-Xu Wei
Zibiao Li
Xiao-Hong Zhao
Meng-Di Yuan
Hai-Lun Gong
Ji-Si-Yu Cheng
Xue-Liang Peng
Lei-Bo Zhang
相关机构
Institute of Materials Research and Engineering, A*STAR (Agency for Science, Technology and Research), 2 Fusionopolis Way, Innovis, #08-03
Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine, Department of Life Sciences and Medicine, Northwest University
Research Unit of Trauma Care, Tissue Repair and Regeneration, Chinese Academy of Medical Sciences
PLA Key Laboratory of Tissue Repair and Regenerative Medicine and Beijing Key Research Laboratory of Skin Injury, Repair and Regeneration, No. 28 Fuxing Road
Research Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Division and 4th Medical Center, PLA General Hospital and PLA Medical College