Hepatitis C: Milestones from discovery to clinical cure

Wei Hu; Chao Zhang; Ji-Jing Shi; Ji-Yuan Zhang; Fu-Sheng Wang

doi:10.1186/s40779-020-00288-y

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Hepatitis C: Milestones from discovery to clinical cure

COMMENTARY | Updated：2023-02-28

- Hepatitis C: Milestones from discovery to clinical cure
- Hepatitis C: Milestones from discovery to clinical cure
- 解放军医学杂志（英文版） 2021年8卷第3期页码：444-446
- Affiliations：
  
  1.Medical School of Chinese PLA, Beijing 100842, China
  2.Department of Infectious Diseases, the Fifth Medical Centre of Chinese PLA General Hospital, National Clinical Research Centre for Infectious Diseases, Beijing 100039, China
  3.The Central Laboratory, the First People’s Hospital of Zhengzhou, Zhengzhou 450004, China
- Author bio：
  
  * fswang302@163.com
- Funds：
- DOI：10.1186/s40779-020-00288-y
  中图分类号：
- 纸质出版：2021-09
- Accepted：
Scan QR Code
Hepatitis C: Milestones from discovery to clinical cure[J]. 解放军医学杂志（英文版）, 2021,8(3):444-446.

Hu et al.: Hepatitis C: milestones from discovery to clinical cure. Mil Med Res, 2020, 7: 59.
Hepatitis C: Milestones from discovery to clinical cure[J]. 解放军医学杂志（英文版）, 2021,8(3):444-446. DOI： 10.1186/s40779-020-00288-y.

Hu et al.: Hepatitis C: milestones from discovery to clinical cure. Mil Med Res, 2020, 7: 59. DOI： 10.1186/s40779-020-00288-y.

摘要

Abstract

On October 5th

2020

Drs. Harvey J. Alter

Michael Houghton and Charles M. Rice were rewarded with Nobel Prize in Physiology or Medicine for "the discovery of hepatitis C virus (HCV)" . During the past 50 years

remarkable achievements have been made in treatment of HCV infection: it has changed from being a life-threatening chronic disease to being curable. In this commentary

we briefly summarized the milestone events in the "scientific journey" from the first report of non-A

non-B hepatitis and discovery of the pathogen (HCV) to final identification of efficacious direct-acting antivirals. Further

we address the challenges and unmet issues in this field.

关键词

Keywords

references

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