Establishment and effectiveness evaluation of a scoring system for exertional heat stroke by retrospective analysis

Meng-Meng Yang; Lu Wang; Yu Zhang; Rui Yuan; Yan Zhao; Jie Hu; Fei-Hu Zhou; Hong-Jun Kang

doi:10.1186/s40779-020-00269-1

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Establishment and effectiveness evaluation of a scoring system for exertional heat stroke by retrospective analysis

RESEARCH | Updated：2023-02-28

- Establishment and effectiveness evaluation of a scoring system for exertional heat stroke by retrospective analysis
- Establishment and effectiveness evaluation of a scoring system for exertional heat stroke by retrospective analysis
- 解放军医学杂志（英文版） 2021年8卷第1期页码：48-61
- Affiliations：
  
  1.Department of Critical Care Medicine, The First Medical Centre, Chinese PLA General Hospital, No. 28, Fuxing Road, Haidian District, Beijing 100853, China
  2.Medical School of Chinese PLA, Beijing, China
- Author bio：
  
  * doctorkang301@126.com; doctorkang301@163.com
- Funds：
  
  the National Natural Science Foundation of China(81671966);the Beijing Natural Science Foundation(7182155);the Application Research and Achievement Extension of Clinical Characteristics in Chinese Capital Foundation(Z171100001017160);the Cultivation Program for Military Medical Science and Technology Youth-Growth Project(16QNP139);the Clinical Research Support Foundation of Chinese PLA General Hospital(2015FC-ZHCG-1002)
- DOI：10.1186/s40779-020-00269-1
  中图分类号：
- 纸质出版：2021-03
- Accepted：
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Establishment and effectiveness evaluation of a scoring system for exertional heat stroke by retrospective analysis[J]. 解放军医学杂志（英文版）, 2021,8(1):48-61.

Yang et al.: Establishment and effectiveness evaluation of a scoring system for exertional heat stroke by retrospective analysis. Mil Med Res, 2020, 7: 40.
Establishment and effectiveness evaluation of a scoring system for exertional heat stroke by retrospective analysis[J]. 解放军医学杂志（英文版）, 2021,8(1):48-61. DOI： 10.1186/s40779-020-00269-1.

Yang et al.: Establishment and effectiveness evaluation of a scoring system for exertional heat stroke by retrospective analysis. Mil Med Res, 2020, 7: 40. DOI： 10.1186/s40779-020-00269-1.

摘要

Abstract

Background:

Heat stroke (HS) is a serious

life-threatening disease. However

there is no scoring system for HS so far. This research is to establish a scoring system that can quantitatively assess the severity of exertional heat stroke (EHS).

Methods:

Data were collected from a total of 170 exertional heat stroke (EHS) patients between 2005 and 2016 from 52 hospitals in China. Univariate statistical methods and comparison of the area under the receiver operating characteristic (ROC) curve (AUC) were used to screen exertional heat stroke score (EHSS) parameters

including but not limited body temperature (T)

Glasgow Coma Scale (GCS) and others. By comparing the sizes of the AUCs of the APACHE II

SOFA and EHSS assessments

the effectiveness of EHSS in evaluating the prognosis of EHS patients was verified.

Results:

Through screening with a series of methods

as described above

the present study determined 12 parameters – body temperature (T)

GCS

lactate (Lac)

platelet count (PLT)

prothrombin time (PT)

fibrinogen (Fib)

troponin I (TnI)

aspartate aminotransferase (AST)

total bilirubin (TBIL)

creatinine (Cr) and acute gastrointestinal injury (AGI) classification – as EHSS parameters. It is a 0–47 point system designed to reflect increasing severity of heat stroke. Low (EHSS<20) and high scores (EHSS>35) showed 100% survival and 100% mortality

respectively. We found that AUCEHSS>AUCSOFA>AUCAPACHE II.

Conclusions:

A total of 12 parameters – T

GCS

Lac

PLT

Fib

TnI

AST

TBIL

Cr and gastrointestinal AGI classification – are the EHSS parameters with the best effectiveness in evaluating the prognosis of EHS patients. As EHSS score increases

the mortality rate of EHS patients gradually increases.

关键词

Keywords

references

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