Role of medical resource level in iodine deficiency disorder

Chen Xu; Zhen Liang; Yong-Jun Luo

doi:10.1186/s40779-017-0126-5

Your Location：

Home >

Browse articles >

Role of medical resource level in iodine deficiency disorder

RESEARCH | Updated：2026-03-12

- Role of medical resource level in iodine deficiency disorder
- Role of medical resource level in iodine deficiency disorder
- MMR 2018年5卷第1期页码：53-61
- Affiliations：
  
  1.Department of Military Medical Geography, College of High Altitude Military Medicine, Third Military Medical University, Chongqing 400038, China
  2.Battalion 5 of Cadet Brigade, Third Military Medical University, Chongqing 400038, China
  3.Key Laboratory of High Altitude Medicine (PLA), Third Military Medical University, Chongqing 400038, China
- Author bio：
  
  *: ajun-333333@gmail.com
- Funds：
  
  the National Natural Science Foundation of China(81372125)
- DOI：10.1186/s40779-017-0126-5
  中图分类号：
- 纸质出版：2018-03
- Accepted：
Scan QR Code
Role of medical resource level in iodine deficiency disorder[J]. MMR, 2018,5(1):53-61.

Xu et al.: Role of medical resource level in iodine deficiency disorder. Mil Med Res, 2017, 4: 18
Role of medical resource level in iodine deficiency disorder[J]. MMR, 2018,5(1):53-61. DOI： 10.1186/s40779-017-0126-5.

Xu et al.: Role of medical resource level in iodine deficiency disorder. Mil Med Res, 2017, 4: 18 DOI： 10.1186/s40779-017-0126-5.

摘要

Abstract

Background:

Iodine deficiency disorders (IDDs) refer to a series of diseases caused by the human body's insufficient iodine intake. Edible salt became iodized in China in 1996

which yielded remarkable results. We have known that IDDs is associated with iodine in the human body

but it is not clear whether IDDs is related to medical resource level.

Methods:

We collected the number of IDDs cases and an index for the level of medical resource from 31 provinces

autonomous regions and municipalities directly under the central government in China. All data came from the China Statistical Yearbook of Health and Family Planning issued in 2013 by the Peking Union Medical College Publishing House. Data standardization and linear regression analysis were used.

Results:

The results showed that IDDs correlated with the number of beds in medical and health institutions

number of medical health personnel

number of medical and health institutions

total health expenditure

average health expenditure per capita

medical insurance for urban resident and new rural cooperative medical rural residents (

0.01). In a multiple linear regression

IDDs was most significantly associated with the number of beds in hospitals

the number of rural health personnel

the number of basic medical and health institutions and government health expenditure for these institutions.

Conclusion:

Based on the experimental data

we concluded that IDDs had a positive connection with the medical resource level

and basic and rural areas had a more significant association with IDDs. This analysis provides new and explicit ideas for iodine prevention and control work in China.

关键词

Keywords

references

Dasgupta PK , Liu Y , Dyke JV . Iodine nutrition: iodine content of iodized salt in the United States . Environ Sci Technol . 2008 ; 42 : 1315 - 23 .

Andersson M , Karumbunathan V , Zimmermann MB . Global iodine status in 2011 and trends over the past decade . J Nutr . 2012 ; 142 : 744 - 50 .

Ma T , Guo J , Wang F . The epidemiology of iodine-deficiency diseases in China . Am J Clin Nutr . 1993 ; 57 : 264S - 6 .

Wu Y , Li X , Chang S , Liu L , Zou S , Hipgrave DB . Variable iodine intake persists in the context of universal salt iodization in China . J Nutr . 2012 ; 142 : 1728 - 34 .

Yang F , Shan Z , Teng X , Li Y , Guan H , Chong W , et al . Chronic iodine excess does not increase the incidence of hyperthyroidism: a prospective community-based epidemiological survey in China . Eur J Endocrinol . 2007 ; 156 : 403 - 8 .

Caron P . Neurocognitive outcomes of children secondary to mild iodine deficiency in pregnant women . Ann Endocrinol (Paris) . 2015 ; 76 : 248 - 52 .

Rose NR , Bonita R , Burek CL . Iodine: an environmental trigger of thyroiditis . Autoimmun Rev . 2002 ; 1 : 97 - 103 .

Zimmermann MB . Iodine requirements and the risks and benefits of correcting iodine deficiency in populations . J Trace Elem Med Biol . 2008 ; 22 : 81 - 92 .

Melse-Boonstra A , Jaiswal N . Iodine deficiency in pregnancy, infancy and childhood and its consequences for brain development . Best Pract Res Clin Endocrinol Metab . 2010 ; 24 : 29 - 38 .

Knudsen N , Laurberg P , Perrild H , Bulow I , Ovesen L , Jorgensen T . Risk factors for goiter and thyroid nodules . Thyroid . 2002 ; 12 : 879 - 88 .

Sun X , Shan Z , Teng W . Effects of increased iodine intake on thyroid disorders . Endocrinol Metab (Seoul) . 2014 ; 29 : 240 - 7 .

Yang J , Zhu L , Li X , Zheng H , Wang Z , Liu Y , et al . Iodine status of vulnerable populations in Henan province of China 2013–2014 after the implementation of the new iodized salt standard . Biol Trace Elem Res . 2016 ; 173 : 7 - 13 .

Chao H , Zhang YF , Liu P , Han YF , Liu SJ . Relationship between Iodine Content in Household Iodized Salt and Thyroid Volume Distribution in Children . Biomed Environ Sci . 2016 ; 29 : 391 - 7 .

Charlton K , Skeaff S . Iodine fortification: why, when, what, how, and who? Curr Opin Clin Nutr Metab Care . 2011 ; 14 : 618 - 24 .

Liu P , Liu SJ , Su XH , Zhang SB , Ji XH . Relationship between urinary iodine and goiter prevalence: results of the Chinese national iodine deficiency disorders survey . J Endocrinol Invest . 2010 ; 33 : 26 - 31 .

Laurberg P , Bulow Pedersen I , Knudsen N , Ovesen L , Andersen S . Environmental iodine intake affects the type of nonmalignant thyroid disease . Thyroid . 2001 ; 11 : 457 - 69 .

Laurberg P , Jorgensen T , Perrild H , Ovesen L , Knudsen N , Pedersen IB , et al . The Danish investigation on iodine intake and thyroid disease, DanThyr: status and perspectives . Eur J Endocrinol . 2006 ; 155 : 219 - 28 .

Adou P , Aka D , Ake M , Koffi M , Tebi A , Diarra-Nama AJ . Assessment of iodine content of dietary salt in Abidjan (Cote d'Ivoire) . Sante . 2002 ; 12 : 18 - 21 .

Luo Y , Kawashima A , Ishido Y , Yoshihara A , Oda K , Hiroi N , et al . Iodine excess as an environmental risk factor for autoimmune thyroid disease . Int J Mol Sci . 2014 ; 15 : 12895 - 912 .

Guastamacchia E , Giagulli VA , Licchelli B , Triggiani V . Selenium and iodine in autoimmune thyroiditis . Endocr Metab Immune Disord Drug Targets . 2015 ; 15 : 288 - 92 .

Harach HR , Escalante DA , Onativia A , Lederer Outes J , Saravia Day E , Williams ED . Thyroid carcinoma and thyroiditis in an endemic goitre region before and after iodine prophylaxis . Acta Endocrinol (Copenh) . 1985 ; 108 : 55 - 60 .

Kolonel LN , Hankin JH , Wilkens LR , Fukunaga FH , Hinds MW . An epidemiologic study of thyroid cancer in Hawaii . Cancer Causes Control . 1990 ; 1 : 223 - 34 .

Kini U , Buch A , Bantwal G . Role of FNA in the medical management of minimally enlarged thyroid . Diagn Cytopathol . 2006 ; 34 : 196 - 200 .

Akdemir B , Oran B , Gunes S , Karaaslan S . Prediction of aortic diameter values in healthy Turkish infants, children, and adolescents by using artificial neural network . J Med Syst . 2009 ; 33 : 379 - 88 .

Hsu HJ , Yen CH , Wu IW , Hsu KH , Chen CK , Sun CY , et al . The association of uremic toxins and inflammation in hemodialysis patients . PLoS One . 2014 ; 9 , e102691 .

Gaitan E . Goitrogens in food and water . Annu Rev Nutr . 1990 ; 10 : 21 - 39 .

Delange F . The disorders induced by iodine deficiency . Thyroid . 1994 ; 4 : 107 - 28 .

Shen H , Liu S , Sun D , Zhang S , Su X , Shen Y , et al . Geographical distribution of drinking-water with high iodine level and association between high iodine level in drinking-water and goitre: a Chinese national investigation . Br J Nutr . 2011 ; 106 : 243 - 7 .

Reinhardt MJ , Moser E . An update on diagnostic methods in the investigation of diseases of the thyroid . Eur J Nucl Med . 1996 ; 23 : 587 - 94 .

Du Y , Gao Y , Meng F , Liu S , Fan Z , Wu J , et al . Iodine deficiency and excess coexist in china and induce thyroid dysfunction and disease: a crosssectional study . PLoS One . 2014 ; 9 : e111937 .

Lv SM , Xie LJ , Zhou RH , Chong ZS , Jia LH , Jing MA , et al . Control of iodine deficiency disorders following 10-year universal salt iodization in Hebei Province of China . Biomed Environ Sci . 2009 ; 22 : 472 - 9 .

Boyages SC , Collins JK , Maberly GF , Jupp JJ , Morris J , Eastman CJ . Iodine deficiency impairs intellectual and neuromotor development in apparentlynormal persons. A study of rural inhabitants of north-central China . Med J Aust . 1989 ; 150 : 676 - 82 .

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

The national and provincial prevalence and non-fatal burdens of diabetes in China from 2005 to 2023 with projections of prevalence to 2050

National age-specific mortality trends for cervical and breast cancers in urban-rural areas of China from 2009 to 2021: a population-based analysis

The evolving burden of heart failure in China: a 34-year subnational analysis of trends and causes from the Global Burden of Disease Study 2023

Establishing integrated chronic non-communicable disease management clinics to address China’s looming health burden