Revascularization and outcomes in Veterans with moderate to severe ischemia on myocardial perfusion imaging

David E. Winchester; Alexander J. Bolanos; Anita Wokhlu; Rebecca J. Beyth; Leslee J. Shaw

doi:10.1186/s40779-017-0121-x

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Revascularization and outcomes in Veterans with moderate to severe ischemia on myocardial perfusion imaging

RESEARCH | Updated：2026-03-12

- Revascularization and outcomes in Veterans with moderate to severe ischemia on myocardial perfusion imaging
- Revascularization and outcomes in Veterans with moderate to severe ischemia on myocardial perfusion imaging
- MMR 2017年4卷第3期页码：127-131
- Affiliations：
  
  1.Malcom Randall VAMC, North Florida/South Georgia Veterans Health System, 1601 SW Archer Rd, Box 111-D, Gainesville, FL, USA
  2.Division of Cardiovascular Medicine, University of Florida College of Medicine, Malcom Randall VAMC, 1601 SW Archer Rd, Box 111-D, Gainesville, FL, USA
  3.Department of Medicine, University of Florida College of Medicine, Gainesville, FL, USA
  4.Division of General Internal Medicine, University of Florida College of Medicine, Gainesville, FL, USA
  5.Division of Cardiology, Emory University School of Medicine, Atlanta, GA, USA
- Author bio：
  
  *: david.winchester@va.gov
- Funds：
  
  the North Florida/South Georgia Veterans Health System in Gainesville, Florida
- DOI：10.1186/s40779-017-0121-x
  中图分类号：
- 纸质出版：2017-09
- Accepted：
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Revascularization and outcomes in Veterans with moderate to severe ischemia on myocardial perfusion imaging[J]. MMR, 2017,4(3):127-131.

Winchester et al.: Revascularization and outcomes in Veterans with moderate to severe ischemia on myocardial perfusion imaging. Mil Med Res, 2017, 4: 12
Revascularization and outcomes in Veterans with moderate to severe ischemia on myocardial perfusion imaging[J]. MMR, 2017,4(3):127-131. DOI： 10.1186/s40779-017-0121-x.

Winchester et al.: Revascularization and outcomes in Veterans with moderate to severe ischemia on myocardial perfusion imaging. Mil Med Res, 2017, 4: 12 DOI： 10.1186/s40779-017-0121-x.

摘要

Abstract

Background:

The prevalence of ischemia on nuclear myocardial perfusion imaging (MPI) has been decreasing. Recent research has questioned the benefit of invasive revascularization for patients with moderate to severe ischemia. We hypothesized that patients with moderate to severe ischemia could routinely undergo successful revascularization.

Methods:

We analyzed data from 544 patients who underwent an MPI at a single academic Veterans Affairs Medical Center. Patients with moderate to severe ischemia

defined as a summed difference score (SDS) 8 or greater

were compared to the rest of the cohort.

Results:

Of the total cohort (

=544)

39 patients had MPI studies with resultant moderate to severe ischemia. Patients with ischemia were more likely to develop coronary artery disease (74.4% versus 38.8%

0.0001) and have successful revascularization (38.5% versus 4.0%

0.0001) during the following year. Revascularization was attempted in 31 patients with moderate to severe ischemia

though only 15(47%) of these attempts were successful. Ischemia was predictive of myocardial infarction (5.1% versus 0.8%

=0.01) within 1 year.

Conclusion:

Moderate to severe ischemia is an uncommon finding in a contemporary nuclear laboratory. Among patients with ischemia

revascularization is typically attempted but is frequently unsuccessful.

Trial registration:

This trial does not appear on a registry as it is neither randomized nor prospective.

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references

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