Advances in the biological effects of terahertz wave radiation

Li Zhao; Yan-Hui Hao; Rui-Yun Peng

doi:10.1186/s40779-014-1-0026-x

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Advances in the biological effects of terahertz wave radiation

REVIEW | Updated：2026-03-12

- Advances in the biological effects of terahertz wave radiation
- Advances in the biological effects of terahertz wave radiation
- MMR 2014年1卷第3期页码：173-176
- Affiliations：
  
  Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing 100850, China
- Author bio：
  
  *: ruiyunpeng18@126.com
- Funds：
- DOI：10.1186/s40779-014-1-0026-x
  中图分类号：
- 纸质出版：2014-09
- Accepted：
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Advances in the biological effects of terahertz wave radiation[J]. MMR, 2014,1(3):173-176.

Zhao et al.: Advances in the biological effects of terahertz wave radiation. Mil Med Res 2014, 1: 26
Advances in the biological effects of terahertz wave radiation[J]. MMR, 2014,1(3):173-176. DOI： 10.1186/s40779-014-1-0026-x.

Zhao et al.: Advances in the biological effects of terahertz wave radiation. Mil Med Res 2014, 1: 26 DOI： 10.1186/s40779-014-1-0026-x.

摘要

Abstract

The terahertz (THz) band lies between microwave and infrared rays in wavelength and consists of non-ionizing radiation. Both domestic and foreign research institutions

including the army

have attached considerable importance to the research and development of THz technology because this radiation exhibits both photon-like and electron-like properties

which grant it considerable application value and potential. With the rapid development of THz technology and related applications

studies of the biological effects of THz radiation have become a major focus in the field of life sciences. Research in this field has only just begun

both at home and abroad. In this paper

research progress with respect to THz radiation

including its biological effects

mechanisms and methods of protection

will be reviewed.

关键词

Keywords

references

Quality of Life and Management of Living Resources Key Action 4 - Environment and Health . [ http://www.frascati.enea.it/THz-BRIDGE/reports/THz-BRIDGE%20Final%20Report.pdf http://www.frascati.enea.it/THz-BRIDGE/reports/THz-BRIDGE%20Final%20Report.pdf ]

Jo SJ , Yoon SY , Lee JY , Kim KT , Jung S , Park J , Park GS , Park WY , Kwon O : Biological effects of femtosecond-terahertz pulses on C57BL/6 mouse skin . Ann Dermatol 2014 , 26 : 129 - 132 .

Feng H , Li F , Chen TN : Current situation and future trends for THz-biomedicine . J Thz Sci Electron Inf Technol 2013 , 11 : 827 - 835 .

Wilmink GJ , Rivest BD , Ibey BL , Roach WP : Determination of death thresholds and identification of terahertz (THz) specific gene expression signatures. Lasers Surg Med 2010 , 42 Suppl. 22 (17) .

Wilmink GJ , Rivest BD , Roth CC , Ibey BL , Payne JA , Cundin LX , Grundt JE , Peralta X , Mixon DG , Roach WP : In vitro investigation of the biological effects associated with human dermal fibroblasts exposed to 2.52 THz radiation . Lasers Surg Med 2011 , 43 : 152 - 163 .

Bourne N , Clothier RH , D’Arienzo M , Harrison P : The effects of terahertz radiation on human keratinocyte primary cultures and neural cell cultures . Altern Lab Anim 2008 , 36 : 667 - 684 .

Ol'shevskaia IuS , Kozlov AS , Petrov AK , Zapara TA , Ratushniak AS : Influence of terahertz (submillimeter) laser radiation on neurons in vitro . ZhVysshNervDeiatIm I P Pavlova 2009 , 59 : 353 - 359 .

Clothier RH , Bourne N : Effects of THz exposure on human primary keratinocyte differentiation and viability . J Biol Phys 2003 , 29 : 179 - 185 .

Zeni O , Gallerano GP , Perrotta A , Romanò M , Sannino A , Sarti M , D’Arienzo M , Doria A , Giovenale E , Lai A , Messina G , Scarfì MR : Cytogenetic observations in human peripheral blood leukocytes following in vitro exposure to THz radiation: a pilot study . Health Phys 2007 , 92 : 349 - 357 .

Williams R , Schofield A , Holder G , Downes J , Edgar D , Harrison P , Siggel-King M , Surman M , Dunning D , Hill S , Holder D , Jackson F , Jones J , McKenzie J , Saveliev Y , Thomsen N , Williams P , Weightman P : The influence of high intensity terahertz radiation on mammalian cell adhesion, proliferation and differentiation . Phys Med Biol 2013 , 58 : 373 - 391 .

Hintzsche H , Jastrow C , Kleine-Ostmann T , Stopper H , Schmid E , Schrader T : Terahertz radiation induces spindle disturbances in human-hamster hybrid cells . Radiat Res 2011 , 175 : 569 - 574 .

Alexandrov BS , Gelev V , Bishop AR , Usheva A , Rasmussen KO : DNA breathing dynamics in the presence of a terahertz field . Phys Lett A 2010 , 374 : 1214 .

Bock J , Fukuyo Y , Kang S , Phipps ML , Alexandrov LB , Rasmussen KØ , Bishop AR , Rosen ED , Martinez JS , Chen HT , Rodriguez G , Alexandrov BS , Usheva A : Mammalian stem cells reprogramming in response to terahertz radiation . PLoS One 2010 , 5 : e15806 .

Alexandrov BS , Rasmussen KØ , Bishop AR , Usheva A , Alexandrov LB , Chong S , Dagon Y , Booshehri LG , Mielke CH , Phipps ML , Martinez JS , Chen HT , Rodriguez G : Non-thermal effects of terahertz radiation on gene expression in mouse stem cells . Biomed Opt Express 2011 , 2 : 2679 - 2689 .

Alexandrov BS , Phipps ML , Alexandrov LB , Booshehri LG , Erat A , Zabolotny J , Mielke CH , Chen HT , Rodriguez G , Rasmussen KØ , Martinez JS , Bishop AR , Usheva A : Specificity and heterogeneity of terahertz radiation effect on gene expression in mouse mesenchymal stem cells . Sci Rep 2013 , 3 : 1184 .

Korenstein-Ilan A , Barbul A , Hasin P , Eliran A , Gover A , Korenstein R : Terahertz radiation increases genomic instability in human lymphocytes . Radiat Res 2008 , 170 : 224 - 234 .

Titova LV , Ayesheshim AK , Golubov A , Rodriguez-Juarez R , Woycicki R , Hegmann FA , Kovalchuk O : Intense THz pulses down-regulate genes associated with skin cancer and psoriasis: a new therapeutic avenue? Sci Rep 2013 , 3 : 2363 .

Titova LV , Ayesheshim AK , Golubov A , Fogen D , Rodriguez-Juarez R , Hegmann FA , Kovalchuk O : Intense THz pulses cause H2AX phosphorylation and activate DNA damage response in human skin tissue . Biomed Opt Express 2013 , 4 : 559 - 568 .

Kim KT , Park J , Jo SJ , Jung S , Kwon OS , Gallerano GP , Park WY , Park GS : High-power femtosecond-terahertz pulse induces a wound response in mouse skin . Sci Rep 2013 , 3 : 2296 .

Demidova EV , Goryachkovskaya TN , Malup TK , Bannikova SV , Semenov AI , Vinokurov NA , Kolchanov NA , Popik VM , Peltek SE : Studying the non-thermal effects of terahertz radiation on E. coli/pKatG-GFP biosensor cells . Bioelectromagnetics 2013 , 34 : 15 - 21 .

Hintzsche H , Jastrow C , Kleine-Ostmann T , Kärst U , Schrader T , Stopper H : Terahertz electromagnetic fields (0.106 THz) do not induce manifest genomic damage in vitro . PLoS One 2012 , 7 : e46397 .

Hintzsche H , Jastrow C , Heinen B , Baaske K , Kleine-Ostmann T , Schwerdtfeger M , Shakfa MK , Kärst U , Koch M , Schrader T , Stopper H : Terahertz radiation at 0.380 THz and 2.520 THz does not lead to DNA damage in skin cells in vitro . Radiat Res 2013 , 179 : 38 - 45 .

Liu YY , Wu FP , Chen YJ , Zhang CL , Geng YZ , Li FL : Experimental studies on terahertz spectrum of stealthy materials . LASER &InFRARED 2009 , 39 : 618 - 621 .

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