Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience

Rabea Dettmer; Alice Rovai; Willem Wolkers; Rainer Blasczyk; Constanca Figueiredo

doi:10.1016/j.mmr.2026.100057

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Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience

LETTER TO THE EDITOR | Updated：2026-09-09

- Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience
- Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience
- 军事医学研究（英文） 2026年
- Affiliations：
  
  Institute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, 30625 Hannover, Germany
  Biostabilization laboratory - Lower Saxony Centre for Biomedical Engineering, Implant Research and Development, University of Veterinary Medicine Hannover, 30559 Hannover, Germany
  Unit for Reproductive Medicine- Clinic for Horses, University of Veterinary Medicine Hannover, 30559 Hannover, Germany
- Author bio：
  
  *Rabea Dettmer, dettmer.rabea@mh-hannover.de
  Constanca Figueiredo, Figueiredo.constanca@mh-hannover.de
- Funds：
  
  the Federal Office of Bundeswehr Equipment, Information Technology and Use(BAAINBw MHH-HF-ZB3-2024)
- DOI：10.1016/j.mmr.2026.100057
  中图分类号：
- 收稿：2026-03-17，
  
  录用：2026-07-23，
  
  纸质出版：2026-08
- Accepted：
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Rabea Dettmer, Alice Rovai, Willem Wolkers, 等. Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience[J/OL]. 军事医学研究（英文）, 2026.

Dettmer R, Rovai A, Wolkers W, Blasczyk R, Figueiredo C. Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience. Mil Med Res. 2026;13(1):100057.
Rabea Dettmer, Alice Rovai, Willem Wolkers, 等. Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience[J/OL]. 军事医学研究（英文）, 2026. DOI： 10.1016/j.mmr.2026.100057.

Dettmer R, Rovai A, Wolkers W, Blasczyk R, Figueiredo C. Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience. Mil Med Res. 2026;13(1):100057. DOI： 10.1016/j.mmr.2026.100057.

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Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience

Scalable bioreactor manufacturing of iPSC-derived megakaryocytes with Proanthocyanidin A supplementation: a strategic platform for military blood supply resilience

DOI：10.1016/j.mmr.2026.100057