Changes of Skelectal Muscle Cellular Membrane Potential during Hemorrhagic Shock and Its Relationship with Functional Disturbances of Cells
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Changes of Skelectal Muscle Cellular Membrane Potential during Hemorrhagic Shock and Its Relationship with Functional Disturbances of Cells
Changes of Skelectal Muscle Cellular Membrane Potential during Hemorrhagic Shock and Its Relationship with Functional Disturbances of Cells
解放军医学杂志(英文版)1986年第2期 页码:135-141
Affiliations:
1. Institute of Surgical Research Third Military Medical College
2. ,Chongqing
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纸质出版:1986
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Changes of Skelectal Muscle Cellular Membrane Potential during Hemorrhagic Shock and Its Relationship with Functional Disturbances of Cells[J]. 解放军医学杂志(英文版), 1986,(2):135-141.
[1]汪江淮,陆熙昶,刘光海,陆松敏,郭素清,侯淦泉,玉成英.Changes of Skelectal Muscle Cellular Membrane Potential during Hemorrhagic Shock and Its Relationship with Functional Disturbances of Cells[J].Journal of Medical Colleges of PLA,1986(02):135-141.
Changes of Skelectal Muscle Cellular Membrane Potential during Hemorrhagic Shock and Its Relationship with Functional Disturbances of Cells[J]. 解放军医学杂志(英文版), 1986,(2):135-141.DOI:
[1]汪江淮,陆熙昶,刘光海,陆松敏,郭素清,侯淦泉,玉成英.Changes of Skelectal Muscle Cellular Membrane Potential during Hemorrhagic Shock and Its Relationship with Functional Disturbances of Cells[J].Journal of Medical Colleges of PLA,1986(02):135-141.DOI:
Changes of Skelectal Muscle Cellular Membrane Potential during Hemorrhagic Shock and Its Relationship with Functional Disturbances of Cells
摘要
Abstract
<正> The changes of skeletal muscle cellular membrane potential(SMCMP)were determined in vivo with the technique of“semi-floating”glass mic-roelectrode in different phases of irreversible hemorrhagic shock in rab-bits.The distribution of extra-and intracellular electrolytes and waterwas studied at the same time.It was found that SMCMP decreased significantly as soon as hypoten-sion occurred
the potential continued to decrease as shock becameprogressively worse
and the leakage of intracellular potassium and reten-tion of intracellular sodium and water occurred 3 hours after the onsetof shock.These facts indicate that the functions of cellular membranebegin to deteriorate in the early stage of shock
the deterioration of thefunctions of the cell proper supervenes as shock progresses
and eventual-ly the cell fails to regulate their volume.
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