1. Lipid Peroxidation Damage Research Group and Burn Department First Affiliated Hospital
2. First Medical College of PLA
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纸质出版:1988
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Burn and Damage by Lipid Peroxidation[J]. 解放军医学杂志(英文版), 1988,(1):55-59.
[1]陈瑗,周玫,齐凤菊,孔华,吴文安,郝廷智,周伟明.Burn and Damage by Lipid Peroxidation[J].Journal of Medical Colleges of PLA,1988(01):55-59.
Burn and Damage by Lipid Peroxidation[J]. 解放军医学杂志(英文版), 1988,(1):55-59.DOI:
[1]陈瑗,周玫,齐凤菊,孔华,吴文安,郝廷智,周伟明.Burn and Damage by Lipid Peroxidation[J].Journal of Medical Colleges of PLA,1988(01):55-59.DOI:
Burn and Damage by Lipid Peroxidation
摘要
Abstract
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正
>
In this study
the plasma and erythrocyte(RBC)lipoperoxidation rates
the contents of antioxidant vitamin E(VE)and the activities of antioxidationenzyme SeGSHP
x
of plasma and RBC in the patients with burn were determinedon the 1st
3rd
5th
10th and 15th days after burn.The results showed that ascompared with healthy subjects
the contents of Iipoperoxide were increased
and thelevels of VE and the activities of SeGSHP
x
were decreased significantly.Thechanges became more significant with the time elapsing
and the most significantchanges were on the 10tb days postburn.In the meantime the percentages of RBCspontaneous hemolysis and the activities of SeGSHPx were increased
and thecontents of VE in RBC were decreased markedly.The regularity of the changes inthe lipoperoxidation rates of plasma and RBC was in accordance with that in thecontents of VE in them.The degrees of the changes in the LPO and VE contentsand the SeGSHPx activities in plasma were in relation to the extents of burn.Onthe 53th
65th and 85th days during recovery postburn
the changes were stillsignificant compared to the healthy subjects
although they had a tendency torestore.
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