Effects of Hemorrhagic Fever Renal Syndrome Virus on Human Bone Marrow Cells Virus on Human Bone marrow Cells
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Effects of Hemorrhagic Fever Renal Syndrome Virus on Human Bone Marrow Cells Virus on Human Bone marrow Cells
Effects of Hemorrhagic Fever Renal Syndrome Virus on Human Bone Marrow Cells Virus on Human Bone marrow Cells
Military Medical Research1986年第4期 页码:377-381
Affiliations:
1. Department of Infectious Diseases Second Affiliated Hospital
2. Fourth Military Medical College.,Xi’an
Author bio:
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DOI:
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纸质出版:1986
Accepted:
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Effects of Hemorrhagic Fever Renal Syndrome Virus on Human Bone Marrow Cells Virus on Human Bone marrow Cells[J]. Military Medical Research, 1986,(4):377-381.
[1]陈思毅,杨为松,张文彬,白雪帆,杨凤仪.Effects of Hemorrhagic Fever Renal Syndrome Virus on Human Bone Marrow Cells Virus on Human Bone marrow Cells[J].Journal of Medical Colleges of PLA,1986(04):377-381.
Effects of Hemorrhagic Fever Renal Syndrome Virus on Human Bone Marrow Cells Virus on Human Bone marrow Cells[J]. Military Medical Research, 1986,(4):377-381.DOI:
[1]陈思毅,杨为松,张文彬,白雪帆,杨凤仪.Effects of Hemorrhagic Fever Renal Syndrome Virus on Human Bone Marrow Cells Virus on Human Bone marrow Cells[J].Journal of Medical Colleges of PLA,1986(04):377-381.DOI:
Effects of Hemorrhagic Fever Renal Syndrome Virus on Human Bone Marrow Cells Virus on Human Bone marrow Cells
摘要
Abstract
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The effects of hemorrhagic fever renal syndrome(HFRS)viruson bone marrow cells are discussed in this paper.Viral antigenicfluorescence in immature marrow cells
especially in megakaryocy-tes
was found in 34 of 45 patients with HFRS by means of IFAand FA.The suspension of marrow cells of 10 patients with HFRSwas inoculated into a flask with Vero-E
6
cells.The strains of HFRSvirus were isolated.Constructural abnormality of bone marrow cellsand virus-like particles were observed in dilated channel of roughendoplasmic reticulum and Golgi apparatus by electron microscopy.These results suggest that human bone marrow cells are one of targetcells which are attacked by HFRS virus and that the virus multip-lication in bone marrow cells can cause a damage of immature cellsand a severe thromocytopenia.
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