Pathological Study of Noncirrhotic Hepatocellular Carcinoma:Its Etiology and Histogenesis

陶文照; 吴存忠; 王建军; 王能进; 邵龙琪; 曾庆镒; 彭宝珍; 吴高德

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Pathological Study of Noncirrhotic Hepatocellular Carcinoma:Its Etiology and Histogenesis

Updated：2026-03-12

- Pathological Study of Noncirrhotic Hepatocellular Carcinoma:Its Etiology and Histogenesis
- Pathological Study of Noncirrhotic Hepatocellular Carcinoma:Its Etiology and Histogenesis
- Military Medical Research 1986年第4期页码：348-355
- Affiliations：
  
  Department of Patho-anatomy Second Military Medical College.,Shanghai
- Author bio：
- Funds：
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- 纸质出版：1986
- Accepted：
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Pathological Study of Noncirrhotic Hepatocellular Carcinoma:Its Etiology and Histogenesis[J]. Military Medical Research, 1986,(4):348-355.

[1]陶文照,吴存忠,王建军,王能进,邵龙琪,曾庆镒,彭宝珍,吴高德.Pathological Study of Noncirrhotic Hepatocellular Carcinoma:Its Etiology and Histogenesis[J].Journal of Medical Colleges of PLA,1986(04):348-355+405.
Pathological Study of Noncirrhotic Hepatocellular Carcinoma:Its Etiology and Histogenesis[J]. Military Medical Research, 1986,(4):348-355. DOI：

[1]陶文照,吴存忠,王建军,王能进,邵龙琪,曾庆镒,彭宝珍,吴高德.Pathological Study of Noncirrhotic Hepatocellular Carcinoma:Its Etiology and Histogenesis[J].Journal of Medical Colleges of PLA,1986(04):348-355+405. DOI：

摘要

Abstract

<正> This work was undertaken to investigate the etiology and histo-genesis of non-cirrhotic hepatocellular car-cinoma（NCH）in humanbeings.Among the 142 cases of NCH studied

135 were samplesobtained from surgical resection and 7 from autopsy.Fifty speci-mens from cirrhotic hepatocellular carcinoma（CH）were taken ascontrol(42 from operated material and 8 from autoptic material.

The results were as follows:1.Hepatitis B liver diseases and Orcein negative hepatitis liverdiseases accounted for 51.41% and 48.59% in NCH group

and 58.00%and 42.00% in CH group

suggesting that the two groups had asimilar background of liver diseases.2.The proliferation of oval cells was found to be 80.99% inNCH group and 100% in CH group（the difference was statisticallysignificant）.It is suggested that oval cells exposed to carcinogensmight develop into poorly differentiated and adenoid type of livercancer.3.Hepatocyte dysplasia was found to be 29.57% and 70.00%in NCH and CH group respectively

and there was a significantdifference between the two groups of HCC.We believe that dys-plasia may be a precancerous disorder.

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