Electrophysiological and Histopathological Studies on Cochlear Changes Induced by Iron Deficiency in Rats

孙爱华; 萧轼之; 李宝实; 郑尊; 李兆基; 王通义; 张义声

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Electrophysiological and Histopathological Studies on Cochlear Changes Induced by Iron Deficiency in Rats

Updated：2026-03-12

- Electrophysiological and Histopathological Studies on Cochlear Changes Induced by Iron Deficiency in Rats
- Electrophysiological and Histopathological Studies on Cochlear Changes Induced by Iron Deficiency in Rats
- 解放军医学杂志（英文版） 1987年第2期页码：91-94
- Affiliations：
  
  1. Department of Otolaryngology Changhai Hospital
  2. Second Military Medical College
  3. ,Shanghai
- Author bio：
- Funds：
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- 纸质出版：1987
- Accepted：
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Electrophysiological and Histopathological Studies on Cochlear Changes Induced by Iron Deficiency in Rats[J]. 解放军医学杂志（英文版）, 1987,(2):91-94.

[1]孙爱华,萧轼之,李宝实,郑尊,李兆基,王通义,张义声.Electrophysiological and Histopathological Studies on Cochlear Changes Induced by Iron Deficiency in Rats[J].Journal of Medical Colleges of PLA,1987(02):91-94+190.
Electrophysiological and Histopathological Studies on Cochlear Changes Induced by Iron Deficiency in Rats[J]. 解放军医学杂志（英文版）, 1987,(2):91-94. DOI：

[1]孙爱华,萧轼之,李宝实,郑尊,李兆基,王通义,张义声.Electrophysiological and Histopathological Studies on Cochlear Changes Induced by Iron Deficiency in Rats[J].Journal of Medical Colleges of PLA,1987(02):91-94+190. DOI：

摘要

Abstract

<正> We report a new animal model of cochlear changes induced by irondeficiency.The experimental studies were conducted in 141 rats fed with basiciron-deficient diet for 7 to 100 days

and 130 normal or chronically anemic ratswere used as controls.Electrophysiological findings showed that the incidence ofover 15 dB auditory threshold elevation was 31.85% in the iron-deficient rats ascompared with zero percent in controls.The main cochlear histopathologicalchanges induced by iron deficiency were strial atrophy and reduction of spiralganglion cells.We conclude that the observed anomalies should be attributed tocochlear tissue iron deficiency.

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