Significance of Clinicopathology in Quantitative Measurement of DNA Content in Hepatocellular Carcinoma
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Significance of Clinicopathology in Quantitative Measurement of DNA Content in Hepatocellular Carcinoma
Significance of Clinicopathology in Quantitative Measurement of DNA Content in Hepatocellular Carcinoma
解放军医学杂志(英文版)1988年第2期 页码:153-156
Affiliations:
1. Institute of Hepatobiliary Surgery Second Military Medical College
2. ,Shanghai
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纸质出版:1988
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Significance of Clinicopathology in Quantitative Measurement of DNA Content in Hepatocellular Carcinoma[J]. 解放军医学杂志(英文版), 1988,(2):153-156.
[1]丛文铭,吴孟超.Significance of Clinicopathology in Quantitative Measurement of DNA Content in Hepatocellular Carcinoma[J].Journal of Medical Colleges of PLA,1988(02):153-156.
Significance of Clinicopathology in Quantitative Measurement of DNA Content in Hepatocellular Carcinoma[J]. 解放军医学杂志(英文版), 1988,(2):153-156.DOI:
[1]丛文铭,吴孟超.Significance of Clinicopathology in Quantitative Measurement of DNA Content in Hepatocellular Carcinoma[J].Journal of Medical Colleges of PLA,1988(02):153-156.DOI:
Significance of Clinicopathology in Quantitative Measurement of DNA Content in Hepatocellular Carcinoma
摘要
Abstract
<正> DNA content of 38 hepatocellular carcinomas (HCC) was quantitativelydetermined by means of image analysis technology.The results showed that DNA contentin HCC was correlated well with the tumor size
capsule breaking
cancerous thrombusforming and clinical prognosis
that is
the higher DNA content was
the more malignanceappeared
but not with the clinical staging and pathological grading of HCC.66.7% ofDNA diploid/near diploid HCC were less than or equal to 3 cm in diameter
whereas 75%of DNA aneuploid HCC were more than 3cm in diameter (P<0.05)
suggesting that HCC at3cm in size may be an important period when the change of biological characteristics wouldoccur.This study indicates that the quantitative analysis of DNA content can provide avaluable supplement to morphology in predicting the biological features and objective basesfor assessing clinical prognosis of HCC.
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