Gastric Mucosal Blood Flow and Acid Secretion in Rats

李兆申; 周岱云; 许国铭

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Gastric Mucosal Blood Flow and Acid Secretion in Rats

Updated：2026-03-12

- Gastric Mucosal Blood Flow and Acid Secretion in Rats
- Gastric Mucosal Blood Flow and Acid Secretion in Rats
- 解放军医学杂志（英文版） 1989年第3期页码：259-262
- Affiliations：
  
  Department of Gastroenterology Changhai Hospital Second Military Medical University Shanghai
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- 纸质出版：1989
- Accepted：
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Gastric Mucosal Blood Flow and Acid Secretion in Rats[J]. 解放军医学杂志（英文版）, 1989,(3):259-262.

[1]李兆申,周岱云,许国铭.Gastric Mucosal Blood Flow and Acid Secretion in Rats[J].Journal of Medical Colleges of PLA,1989(03):259-262.
Gastric Mucosal Blood Flow and Acid Secretion in Rats[J]. 解放军医学杂志（英文版）, 1989,(3):259-262. DOI：

[1]李兆申,周岱云,许国铭.Gastric Mucosal Blood Flow and Acid Secretion in Rats[J].Journal of Medical Colleges of PLA,1989(03):259-262. DOI：

摘要

Abstract

<正> The relationship between gastric mucosal blood flow （GMBF） and gastric acid secretionwere studied in rats by using secretory stimulant （pentagastrin）and inhibitor（cimetidine）. GMBFwas measured by Laser Doppler flowmetry （LDF） and gastric mucosal pH determined by microglasspH electrode. GMBF increased and gastric mucosal pH decreased significantly after intravenous injec-tion of 6μg/kg of pentagastrin; nevertheless GMBF decreased and gastric mucosal pH increasedmarkedly after intravenous administration of 100mg/kg of cimetidine. This indicates that pentagastrincan increase GMBF and gastric acid secretion

and cimetidine can decrease GMBF and gastric acidsecretion in rats

proving the close relationship between GMBF and gastric acid secretion in rats.

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