Effects of Ginsenosides and Ketoprofen on Smoke Inhalation Injury in Rabbits and Rats
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Effects of Ginsenosides and Ketoprofen on Smoke Inhalation Injury in Rabbits and Rats
Effects of Ginsenosides and Ketoprofen on Smoke Inhalation Injury in Rabbits and Rats
解放军医学杂志(英文版)1989年第3期 页码:282-284
Affiliations:
Departments of Pharmacology and Pathology Third Military Medical College Chongqing
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纸质出版:1989
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Effects of Ginsenosides and Ketoprofen on Smoke Inhalation Injury in Rabbits and Rats[J]. 解放军医学杂志(英文版), 1989,(3):282-284.
[1]黄钺华,张敏,王传年,李元平,史景泉,许平庆.Effects of Ginsenosides and Ketoprofen on Smoke Inhalation Injury in Rabbits and Rats[J].Journal of Medical Colleges of PLA,1989(03):282-284.
Effects of Ginsenosides and Ketoprofen on Smoke Inhalation Injury in Rabbits and Rats[J]. 解放军医学杂志(英文版), 1989,(3):282-284.DOI:
[1]黄钺华,张敏,王传年,李元平,史景泉,许平庆.Effects of Ginsenosides and Ketoprofen on Smoke Inhalation Injury in Rabbits and Rats[J].Journal of Medical Colleges of PLA,1989(03):282-284.DOI:
Effects of Ginsenosides and Ketoprofen on Smoke Inhalation Injury in Rabbits and Rats
摘要
Abstract
<
正
>
Six hours after smoke inhalation injury in rabbits
the permeability of pulmonary vesselsand the aggregation of circulating platelets increased markedly accompanied with apparent patholog-ical changes in the trachea and lungs. Fifteen minutes after smoke inhalation injury in rabbits
an intravenous dose of ginsenosides or ketoprofenwas given to the animals respectively. 6 hours after medication
it was found that both the drugscould significantly alleviate the platelet aggregation
but only ginsenosides could alleviate theaugmentation of pulmonary vascular permeability and the pathological lesions in the trachea andlungs. In those rats injured by smoke inhalation
l hour after an intravenous dose of ginsenosides
theplasma PGI
2
level was elevated and TXA
2
/PGI
2
ratio decreased significantly.
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