Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma
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Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma
Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma
解放军医学杂志(英文版)1989年第1期 页码:21-24
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Institute of Hepatobiliary Surgery Changhai Hospital Second Military Medical University Shanghai
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纸质出版:1989
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Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma[J]. 解放军医学杂志(英文版), 1989,(1):21-24.
[1]杨甲梅,吴孟超,陈汉.Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma[J].Journal of Medical Colleges of PLA,1989(01):21-24.
Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma[J]. 解放军医学杂志(英文版), 1989,(1):21-24.DOI:
[1]杨甲梅,吴孟超,陈汉.Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma[J].Journal of Medical Colleges of PLA,1989(01):21-24.DOI:
Evaluation of α-L-Fucosidase in the Diagnosis of Primary Hepatic Carcinoma
摘要
Abstract
<正> α-L-fucosidasc (AFU) activity was determined by referring to Troost’s method in sera
liv-er tissues and lesions from patients with hepatoccllular carcinoma (HCC)
other liverspace-occupying lesions (SOL) and diseases. The results showed that the sensitivity and specificityfor the diagnosis of HCC were 81.2% and 83. 3% respectively with the assay of serum AFU activi-ty
and sensitivities in the diagnosis of AFP-negative and early HCC were 76.1% and 70. 8%
respectively. The AFU activity in the HCC tissues and their pericancerous liver tissues was twice asmuch as controls
and consisted with their serum AFU activity (r=0. 742
P<0.01). It is sug-gested that AFU could be a new biologic marker of HCC and have an important value in thediagnosis of HCC.
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