A Morphometric Study of the Lungs after Blast lnjury in Rats
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A Morphometric Study of the Lungs after Blast lnjury in Rats
A Morphometric Study of the Lungs after Blast lnjury in Rats
解放军医学杂志(英文版)1989年第2期 页码:135-140
Affiliations:
1. Department No.4 Research Institute of Surgery
2. Third Military Medical College
3. ,Chongqing
Author bio:
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DOI:
中图分类号:
纸质出版:1989
Accepted:
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A Morphometric Study of the Lungs after Blast lnjury in Rats[J]. 解放军医学杂志(英文版), 1989,(2):135-140.
[1]赵敏,王正国,刘大维,张清华,王声文,周萍.A Morphometric Study of the Lungs after Blast lnjury in Rats[J].Journal of Medical Colleges of PLA,1989(02):135-140.
A Morphometric Study of the Lungs after Blast lnjury in Rats[J]. 解放军医学杂志(英文版), 1989,(2):135-140.DOI:
[1]赵敏,王正国,刘大维,张清华,王声文,周萍.A Morphometric Study of the Lungs after Blast lnjury in Rats[J].Journal of Medical Colleges of PLA,1989(02):135-140.DOI:
A Morphometric Study of the Lungs after Blast lnjury in Rats
摘要
Abstract
<正> A lot of research work has been carriod out on thc lungs after blast injury
but nomorphomctric study of the blast-injured lungs has ever been reported so far.The authors quantifiedthe morphological changes of the lungs with blast injury in rats with stereological methods.t wasfound that following the blast injury
the pulmonary capillary volume and the intcmal surface arca de-creased significantly
while the arithmetic and harmonic mean thickness of the air-blood barrier andthe volume of polymorphonuclear leucocytes and platelets in the capillaries incrcased markedly.Themorphometric oxygen diffusion capacity of the lungs was remarkably reduced mainly due to the de-crease of the conductance of the air-blood barrier and erythrocytcs.In addition
the changes of theoxygen diffussion capacity of the lungs were closely related to the partial pressure of arteria/blood oxy-gen.These facts imply that the damage to the pulmonary capillaries was one of the main causes ofalveolar bleeding and early respiratory insufficiency.It is possible that a mathematic relationshipcould be established between the intensity of the blast impact and the consequent morphologicalchanges of the injured lungs.
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