The Role of Ca<sup>2+</sup> and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion

宋烈昌; 周廷冲

Your Location：

Home >

Browse articles >

The Role of Ca²⁺ and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion

Updated：2026-03-12

- The Role of Ca²⁺ and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion
- The Role of Ca²⁺ and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion
- 解放军医学杂志（英文版） 1989年第1期页码：9-12
- Affiliations：
  
  1. Nanfang Hospital First Military Medical University Guangzhou
  2. Institute of Basic Medical Sciences Academy of Military Medical Sciences Beijing
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：1989
- Accepted：
Scan QR Code
The Role of Ca²⁺ and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion[J]. 解放军医学杂志（英文版）, 1989,(1):9-12.

[1]宋烈昌,周廷冲.The Role of Ca~(2+) and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion[J].Journal of Medical Colleges of PLA,1989(01):9-12.
The Role of Ca²⁺ and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion[J]. 解放军医学杂志（英文版）, 1989,(1):9-12. DOI：

[1]宋烈昌,周廷冲.The Role of Ca~(2+) and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion[J].Journal of Medical Colleges of PLA,1989(01):9-12. DOI：

摘要

Abstract

正

PK11195

a ligand of peripheral-type benzodiazepine receptor can stimulate thealdosterone secretion of isolated adrenal glomerulosa cell: this effect could be abolished by nifedipinewhich mainly blocks the calcium channel in plasma membrane

but could not be abolished bydantrolene

a selective blocker of mitochondria calcium channel. Even under the condition of themaximum stimulative effects on aldosterone secretion

PK11195 could not change the cyclic AMP（cAMP） content in isolated glomerulosa cells. These results indicated that in the modulatory mecha-nism of benzodiazepine receptor on aldosterone secretion

the intracellular messenger might be theCa

from extracellular Ca

pool

but not the Ca

from mitochondria Ca

pool or cAMP.

关键词

Keywords

references

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

暂无数据

The Role of Ca2+ and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion

The Role of Ca2+ and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion

DOI：

摘要

Abstract

关键词

Keywords

references

The Role of Ca²⁺ and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion

The Role of Ca²⁺ and Cyclic AMP in the Modulation of BenzodiazepineReceptor on Aldosterone Secretion