Changes of Selenium Metabolism Glutathione Peroxidase Activity and Lipid Peroxides Content in Severely Scalding-injured Rats
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Changes of Selenium Metabolism Glutathione Peroxidase Activity and Lipid Peroxides Content in Severely Scalding-injured Rats
Changes of Selenium Metabolism Glutathione Peroxidase Activity and Lipid Peroxides Content in Severely Scalding-injured Rats
解放军医学杂志(英文版)1989年第3期 页码:213-216
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Department of Biochemistry Third Military Medical College Chongqing
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纸质出版:1989
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Changes of Selenium Metabolism Glutathione Peroxidase Activity and Lipid Peroxides Content in Severely Scalding-injured Rats[J]. 解放军医学杂志(英文版), 1989,(3):213-216.
[1]刘泽军,董燕麟.Changes of Selenium Metabolism Glutathione Peroxidase Activity and Lipid Peroxides Content in Severely Scalding-injured Rats[J].Journal of Medical Colleges of PLA,1989(03):213-216.
Changes of Selenium Metabolism Glutathione Peroxidase Activity and Lipid Peroxides Content in Severely Scalding-injured Rats[J]. 解放军医学杂志(英文版), 1989,(3):213-216.DOI:
[1]刘泽军,董燕麟.Changes of Selenium Metabolism Glutathione Peroxidase Activity and Lipid Peroxides Content in Severely Scalding-injured Rats[J].Journal of Medical Colleges of PLA,1989(03):213-216.DOI:
Changes of Selenium Metabolism Glutathione Peroxidase Activity and Lipid Peroxides Content in Severely Scalding-injured Rats
摘要
Abstract
<正> The changes of sclenium metabolism
glutathione peroxidase activity and lipid peroxidescontent in the tissues of rats suffering from 30% TBSA full thickness scalding were observed in thefirst 7 days after injury. It was found that selenium content in the rat tissues decreased remarkably af-ter injury
which in turn resulted in serious reduction of glutathione peroxidasc activity and significantincrease of lipid peroxides in the scrum
crythrocytcs and liver. However the muscular tissue showedno significant changes. These facts imply that after burn injury
the body is in a state of selenium deficiency
the lossof selenium might be responsible for the reduction of anti - peroxidation ability of glutathioneperoxidase
and conscqucntly there is an increase of lipid peroxides in the tissues. Only the musculartissue is insensitive to lipid peroxidation. It is believed that the reduction of anti-peroxidation abilityof glutathione peroxidasc after bum injury might be one of the main causes to intensify
the injury re-suiting from free radicals.
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