The immunocytochemical localization of insulin-like growth factor Ⅱ in human cirrhosis
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The immunocytochemical localization of insulin-like growth factor Ⅱ in human cirrhosis
The immunocytochemical localization of insulin-like growth factor Ⅱ in human cirrhosis
解放军医学杂志(英文版)1992年第3期 页码:279-282
Affiliations:
1. Department of Pathology Fourth Military Medical University
2. ,USA
3. Xijing Hospital
4. Liver Research Center
5. Einstein College of Medicine
Author bio:
Funds:
Supported by the National Natural Science Foundation of China,No.3880376
DOI:
中图分类号:
纸质出版:1992
Accepted:
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The immunocytochemical localization of insulin-like growth factor Ⅱ in human cirrhosis[J]. 解放军医学杂志(英文版), 1992,(3):279-282.
[1]刘彦仿,苏勤,Charles E.Rogler.The immunocytochemical localization of insulin-like growth factor Ⅱ in human cirrhosis[J].Journal of Medical Colleges of PLA,1992(03):279-282.
The immunocytochemical localization of insulin-like growth factor Ⅱ in human cirrhosis[J]. 解放军医学杂志(英文版), 1992,(3):279-282.DOI:
[1]刘彦仿,苏勤,Charles E.Rogler.The immunocytochemical localization of insulin-like growth factor Ⅱ in human cirrhosis[J].Journal of Medical Colleges of PLA,1992(03):279-282.DOI:
The immunocytochemical localization of insulin-like growth factor Ⅱ in human cirrhosis
摘要
Abstract
<正> Sections of 30 cases of human cirrhosis were stained with rabbit anti-insulin-likegrowth factor Ⅱ(IGF Ⅱ)by double PAP method.By the serological examination 15 patientsshowed HBV infection and sections of 14 eases were HBsAg postively with a total rate of 67%(20 cases).The IGF Ⅱ was positive in the cytoplasm of all the liver and ductular cells.Binucle-ated
polypoid liver cells and the peripheral cells of the lobules or nodules were distinctly posi-tive
The liver cells which were strongly positive were a kind of thin polygonal cells with asmall oval or a round deeply stained nucleus in each.They might exist sporadically in the lob-ules or in the marginal portion of a nodule.These liver cells are quite different from the so-called oval cells which are derived from the proliferating ductules and are generally believed tobe responsible for the pathogensis of hepatoma.
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