The change of basic fibroblast growth factor and effect of prostacyclin in lung injury

刘国建; 王正国; 朱佩芳

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The change of basic fibroblast growth factor and effect of prostacyclin in lung injury

Updated：2026-03-12

- The change of basic fibroblast growth factor and effect of prostacyclin in lung injury
- The change of basic fibroblast growth factor and effect of prostacyclin in lung injury
- 解放军医学杂志（英文版） 1992年第1期页码：22-26
- Affiliations：
  
  1. Research Institute of Surgery Third Military Medical College
  2. ,Chongqing,630038
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：1992
- Accepted：
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The change of basic fibroblast growth factor and effect of prostacyclin in lung injury[J]. 解放军医学杂志（英文版）, 1992,(1):22-26.

[1]刘国建,王正国,朱佩芳.The change of basic fibroblast growth factor and effect of prostacyclin in lung injury[J].Journal of Medical Colleges of PLA,1992(01):22-26.
The change of basic fibroblast growth factor and effect of prostacyclin in lung injury[J]. 解放军医学杂志（英文版）, 1992,(1):22-26. DOI：

[1]刘国建,王正国,朱佩芳.The change of basic fibroblast growth factor and effect of prostacyclin in lung injury[J].Journal of Medical Colleges of PLA,1992(01):22-26. DOI：

摘要

Abstract

<正> In this study

the changes in activity and mRNA transcript of basic fibroblast growth fac-tor（bFGF）in lung injury and the effect of prostacyclin on the treatment of lung injury wereinvestigated.The result of the experiment revealed that there were not any bioactive bFGF andbFGF mRNA in the lung tissue of normal dogs.bFGF activity and bFGF mRNA were detectedonly in the injured lung tissue.Prostacyclin could slightly elevate the activity of bFGF andsignificantly elevate the level of bFGF mRNA.The findings suggest that（1）the level of bFGF in-creased after lung injury.（2）Prostacyclin could influence the expression of bFGF.（3）bFGF couldplay an important role in the repair of injury lung tissue.

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