Respiratory Abnormalities Following Smoke Inhalation Injury in the Sheep
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Respiratory Abnormalities Following Smoke Inhalation Injury in the Sheep
Respiratory Abnormalities Following Smoke Inhalation Injury in the Sheep
解放军医学杂志(英文版)1989年第4期 页码:303-311
Affiliations:
1. Research Institute on Burns Third Military Medical College
2. ,Chongqing
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纸质出版:1989
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Respiratory Abnormalities Following Smoke Inhalation Injury in the Sheep[J]. 解放军医学杂志(英文版), 1989,(4):303-311.
[1]王成忠,黎鳌,杨宗城.Respiratory Abnormalities Following Smoke Inhalation Injury in the Sheep[J].Journal of Medical Colleges of PLA,1989(04):303-311+383-384.
Respiratory Abnormalities Following Smoke Inhalation Injury in the Sheep[J]. 解放军医学杂志(英文版), 1989,(4):303-311.DOI:
[1]王成忠,黎鳌,杨宗城.Respiratory Abnormalities Following Smoke Inhalation Injury in the Sheep[J].Journal of Medical Colleges of PLA,1989(04):303-311+383-384.DOI:
Respiratory Abnormalities Following Smoke Inhalation Injury in the Sheep
摘要
Abstract
<
正
>
An arumal model to study smoke inhalation injuries was established in the sheep.22adult mate sheep were forced to inhale saw-dust smoke of pine wood for 6 minutes through anendotracheal tube.Pulmonury compliance
arterial blood gases
carboxyhemoglobin
andoxyhemoglobin were monitored and the morpholgical chanhes of the tracheobronchial tree andpulmonary parenchyma were studied with optical and eletron microscopy.Severe carbon monoxide poisorung with fatal blooa level of carboxyhemoglobin(higher than50%) was found at the end of smoie inhalation.Acute respiratory distress
progressivehypoxerrua decreased pulmonary compliance and increased P(A-α)O
2
and Q
s
/Q
T
oecurred af-ter the injury.Tracheobronchial blockage due to pseudomembranous cast
pulmonary edema
atelectasis
and necrosis of pulmonary epithelium were demonstrated on histological sections.The mechaniisms of carbon monoxide poisoning ane acute respiratory failure was discussed.
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