Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation
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Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation
Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation
解放军医学杂志(英文版)1989年第4期 页码:361-364
Affiliations:
1. the Department of Clinical Immunology of General Hospital of Nanjing Command of PLA Nanjing
2. Second Military Medical University
3. Shanghai and Department of Clinical Immunology,200433
4. ,Nanjing,210002
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纸质出版:1989
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Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation[J]. 解放军医学杂志(英文版), 1989,(4):361-364.
[1]李晓军,武建国.Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation[J].Journal of Medical Colleges of PLA,1989(04):361-364.
Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation[J]. 解放军医学杂志(英文版), 1989,(4):361-364.DOI:
[1]李晓军,武建国.Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation[J].Journal of Medical Colleges of PLA,1989(04):361-364.DOI:
Determination of IgA,IgG,IgM Class-Specific Rheumatoid Factor and Its Clinical Evaluation
摘要
Abstract
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正
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Solid Phase enzyme-linked Immunosorbent assay(ELISA) for detectingclass-specific rheumatoid factor (RF) was established.Aggregated rabbit lgG was used ascoating antigen and the presence of RF was demonstrated by F(ab’)
2
fragment of anti-humanIg conjugated to horseradish peroxidase(HRP).The results showed that high levels ofIgM-RF
IgG-RF and IgA-RF were found in patients with rheumatoid arthritis.A positive cor-relation existed between IgM-
IgG-
IgA-RF and disease activity.The presence of vasculitis al-so correlated positively with the levels of 3 class-specific RFs.
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