Effect of Corocinnarine on Physiological Characteristics of Guinea Pig Papillary Muscles

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- Effect of Corocinnarine on Physiological Characteristics of Guinea Pig Papillary Muscles
- Effect of Corocinnarine on Physiological Characteristics of Guinea Pig Papillary Muscles
- 解放军医学杂志（英文版） 1990年第3期页码：296-299
- Affiliations：
  
  1. Department of Pharmacology Fourth Military Medical University
  2. ,Xi’an,710032
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：1990
- Accepted：
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Effect of Corocinnarine on Physiological Characteristics of Guinea Pig Papillary Muscles[J]. 解放军医学杂志（英文版）, 1990,(3):296-299.

[1]陈水英,赵德化,盛宝恒.Effect of Corocinnarine on Physiological Characteristics of Guinea Pig Papillary Muscles[J].Journal of Medical Colleges of PLA,1990(03):296-299.
Effect of Corocinnarine on Physiological Characteristics of Guinea Pig Papillary Muscles[J]. 解放军医学杂志（英文版）, 1990,(3):296-299. DOI：

[1]陈水英,赵德化,盛宝恒.Effect of Corocinnarine on Physiological Characteristics of Guinea Pig Papillary Muscles[J].Journal of Medical Colleges of PLA,1990(03):296-299. DOI：

正

In our experiment it was found that

in guinea pig papillary muscles

8205 de-creased the automaticity and prolonged the functional refractory period（FRP）as well asdecreased the contractile amplitude dose-dependently

but exerted no effect on the excitabili-ty.The dose-response curves of isoproterenol shifted to the right in parallel manner

inaccordance with competitive antagonistic

but the effect of 8205 was much less than thatof propranolol.Dose-response curves of CaCl

shifted to the right non-parallelly.The re-sults indicated that the mechanism of anti-arrhythmia of 8205 might be related to theCa

-antagonism.

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