Abnormalities of Cellular Immunoregulation in Patients with Epidemic Hemorrhagic Fever
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Abnormalities of Cellular Immunoregulation in Patients with Epidemic Hemorrhagic Fever
Abnormalities of Cellular Immunoregulation in Patients with Epidemic Hemorrhagic Fever
解放军医学杂志(英文版)1990年第2期 页码:106-112
Affiliations:
1. Department of Infectious Diseases Tangdu Hospital
2. Fourth Military Medical University
3. ,Xi’an,710038
Author bio:
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DOI:
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纸质出版:1990
Accepted:
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Abnormalities of Cellular Immunoregulation in Patients with Epidemic Hemorrhagic Fever[J]. 解放军医学杂志(英文版), 1990,(2):106-112.
[1]陈龙邦,杨为松,徐海峰,张文彬,朱平,尚高峰.Abnormalities of Cellular Immunoregulation in Patients with Epidemic Hemorrhagic Fever[J].Journal of Medical Colleges of PLA,1990(02):106-112.
Abnormalities of Cellular Immunoregulation in Patients with Epidemic Hemorrhagic Fever[J]. 解放军医学杂志(英文版), 1990,(2):106-112.DOI:
[1]陈龙邦,杨为松,徐海峰,张文彬,朱平,尚高峰.Abnormalities of Cellular Immunoregulation in Patients with Epidemic Hemorrhagic Fever[J].Journal of Medical Colleges of PLA,1990(02):106-112.DOI:
Abnormalities of Cellular Immunoregulation in Patients with Epidemic Hemorrhagic Fever
摘要
Abstract
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正
>
In this report
a comparative study is made of the function test of spontaneousT suppressor cell(STs)and T Lymphocyte subsets in patients with epidemic hemorrha-gic fever(EHF).It was found that in the early stages of the disease the activity of STs wasmarkedly lower than that of the controls
while the percentage of CD
?
+
cells increasedsignificantly
which led to the decrease and reciprocation of CD
4
/CD
8
ratio
and that theactivity of STs was reversely related to the proportion of CD
8
+
cells on linear regressionanalysis
indicating that the CD
8
+
cells increased may mainly belong to cytotoxic T cells.It was also shown that the changes of STs function and CD
4
/CD
8
ratio were related tothe abnormalities of serum C
3
content and circulating immune complex.The results sug-gest that the disturbance of host cellular immunoregulation may play an important rolein the pathogenesis of EHF.
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