Changes of peroxide dismutase activity and malondialdehyde level in the smooth muscle cells of human fetal aorta cultured in vitro by low density lipoprotein conditional medium

杨仕林; 程娉; 侯双风; 陈瑗; 周玫

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Changes of peroxide dismutase activity and malondialdehyde level in the smooth muscle cells of human fetal aorta cultured in vitro by low density lipoprotein conditional medium

Updated：2026-03-12

- Changes of peroxide dismutase activity and malondialdehyde level in the smooth muscle cells of human fetal aorta cultured in vitro by low density lipoprotein conditional medium
- Changes of peroxide dismutase activity and malondialdehyde level in the smooth muscle cells of human fetal aorta cultured in vitro by low density lipoprotein conditional medium
- 解放军医学杂志（英文版） 1992年第1期页码：77-80
- Affiliations：
  
  1. Departments of Pathology First Militar ty
  2. ,Guangzhou,510515
  3. Biochemistry
  4. First Military Medical University
  5. Medical Protection
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：1992
- Accepted：
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Changes of peroxide dismutase activity and malondialdehyde level in the smooth muscle cells of human fetal aorta cultured in vitro by low density lipoprotein conditional medium[J]. 解放军医学杂志（英文版）, 1992,(1):77-80.

[1]杨仕林,程娉,侯双风,陈瑗,周玫.Changes of peroxide dismutase activity and malondialdehyde level in the smooth muscle cells of human fetal aorta cultured in vitro by low density lipoprotein conditional medium[J].Journal of Medical Colleges of PLA,1992(01):77-80.
Changes of peroxide dismutase activity and malondialdehyde level in the smooth muscle cells of human fetal aorta cultured in vitro by low density lipoprotein conditional medium[J]. 解放军医学杂志（英文版）, 1992,(1):77-80. DOI：

[1]杨仕林,程娉,侯双风,陈瑗,周玫.Changes of peroxide dismutase activity and malondialdehyde level in the smooth muscle cells of human fetal aorta cultured in vitro by low density lipoprotein conditional medium[J].Journal of Medical Colleges of PLA,1992(01):77-80. DOI：

摘要

Abstract

<正> Here are reported the changes of superoxide dismutase（SOD）activity andmalondialdehyde（MDA）in the smooth muscle cells of human fetal aorta cultured in vitro with lowdensity lipoprotein（LDL）conditional medium.The results showed that a single concentration of hu-man LDL（50μg/ml）stimulated proliferation of smooth muscle cells

and the SOD activityof the cells in the experimental group was higher

from the first to the fifth cultured day whenthe cells had a active proliferation

than that of the control cells.This suggests that LDL might in-duce the increase of SOD activity.At the seventh day

as the cells were in inactive proliferation

SOD activity was low and the difference was significant as compared with that at the fifth day ofthe same group.This also indicates that the SOD activity may be related to the cell proliferation.MDA level within the cells of the esperimental group was lowered with the cell active proliferationand the increase of SOD activity

but when the cells were in inactive proliferation and the SOD ac-tivity decreased

it will remained low.

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