Effects of ventromedial hypothalamic somatostatin on gastric somatostatin and acid secretion in rats

曲方; 林葆城; 王成海; 宋朝佑; 白波; 朱鹤年

Your Location：

Home >

Browse articles >

Effects of ventromedial hypothalamic somatostatin on gastric somatostatin and acid secretion in rats

Updated：2026-03-12

- Effects of ventromedial hypothalamic somatostatin on gastric somatostatin and acid secretion in rats
- Effects of ventromedial hypothalamic somatostatin on gastric somatostatin and acid secretion in rats
- 解放军医学杂志（英文版） 1991年第2期页码：141-146
- Affiliations：
  
  1. Department of Neurobiology Second Military Medical University
  2. ,Shanghai,200433
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：1991
- Accepted：
Scan QR Code
Effects of ventromedial hypothalamic somatostatin on gastric somatostatin and acid secretion in rats[J]. 解放军医学杂志（英文版）, 1991,(2):141-146.

[1]曲方,林葆城,王成海,宋朝佑,白波,朱鹤年.Effects of ventromedial hypothalamic somatostatin on gastric somatostatin and acid secretion in rats[J].Journal of Medical Colleges of PLA,1991(02):141-146.
Effects of ventromedial hypothalamic somatostatin on gastric somatostatin and acid secretion in rats[J]. 解放军医学杂志（英文版）, 1991,(2):141-146. DOI：

[1]曲方,林葆城,王成海,宋朝佑,白波,朱鹤年.Effects of ventromedial hypothalamic somatostatin on gastric somatostatin and acid secretion in rats[J].Journal of Medical Colleges of PLA,1991(02):141-146. DOI：

摘要

Abstract

<正> The effects of somatostatin and cysteamine injected into theventromedial nucleus of hypothalamus（VMH）on somatostatin-likeimmunoreactivity（SLI）concentration in the gastric antral mucosa and portal veinplasma

as well as the gastric acid secretion were studied in anesthetized rats.TheSLI concentration in the gastric antral mucosa and portal vein plasma and thegastric acid output were significantly increased one hour after the injection ofsomatostatin（0.5μg/0.5μ1）into the VMH.Four hours later

the SLI concentrationin the mucosa was still higher than the control level

while the SLI level in theplasma and the acid secretion were close to those of controls.On the contrary

the SLI concentration in the mucosa and plasma and the acid output weremarkedly decreased at four hours after the injection of cysteamine（15μg/0.5μ1）into the VMH.The present results suggest that both exogenous and endogenoussomatostatin in the VMH have a facilitatory action on the gastric somatostatinconcentration and its release as well as on the gastric acid secretion

thus provid-ing evidence for hypothalamic control of gastric somatostatin and acid secretion.

关键词

Keywords

references

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

暂无数据