Intestinal metaplasia,dysplasia and gastric cancer:a study of mucohistochemistry,immunohistochemistry and cell DNA quantitative analysis

李春启; 刘为纹; 王伯欧; 李继昌

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Intestinal metaplasia,dysplasia and gastric cancer:a study of mucohistochemistry,immunohistochemistry and cell DNA quantitative analysis

Updated：2026-03-12

- Intestinal metaplasia,dysplasia and gastric cancer:a study of mucohistochemistry,immunohistochemistry and cell DNA quantitative analysis
- Intestinal metaplasia,dysplasia and gastric cancer:a study of mucohistochemistry,immunohistochemistry and cell DNA quantitative analysis
- 解放军医学杂志（英文版） 1992年第2期页码：192-196
- Affiliations：
  
  1. Department of Gastroenterology Southwest Hospital
  2. Third Military Medical College
  3. ,Zhengzhou,450052
  4. Department of Medicine
  5. First Affiliated Hospital
  6. Henan Medical University
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：1992
- Accepted：
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Intestinal metaplasia,dysplasia and gastric cancer:a study of mucohistochemistry,immunohistochemistry and cell DNA quantitative analysis[J]. 解放军医学杂志（英文版）, 1992,(2):192-196.

[1]李春启,刘为纹,王伯欧,李继昌.Intestinal metaplasia,dysplasia and gastric cancer:a study of mucohistochemistry,immunohistochemistry and cell DNA quantitative analysis[J].Journal of Medical Colleges of PLA,1992(02):192-196.
Intestinal metaplasia,dysplasia and gastric cancer:a study of mucohistochemistry,immunohistochemistry and cell DNA quantitative analysis[J]. 解放军医学杂志（英文版）, 1992,(2):192-196. DOI：

[1]李春启,刘为纹,王伯欧,李继昌.Intestinal metaplasia,dysplasia and gastric cancer:a study of mucohistochemistry,immunohistochemistry and cell DNA quantitative analysis[J].Journal of Medical Colleges of PLA,1992(02):192-196. DOI：

摘要

Abstract

<正> One hundred and sixty-eight specimens of intestinal metaplasia（IM）with variousaccompanying lesions in gastric mucosa were studied with mucohistochemical and ABCimmunohistochemical staining

The quantitative analysis of cell DNA was done withflowcytometry for 36 specimens.The results indicated that the incidence of type Ⅱb IM wassignificantly higher in the groups of dysplasia（34.6％）and mucosa adjacent to gastric cancer（GC）（51.7％）than in the chronic atrophic gastritis（CAG）group（16.0％）（P<0.01）.The expres-sion rate of monoclonal antibody MG7 related antigen（MG7-Ag）in type Ⅱb IM（473％）wasalso significantly higher than those in type la（29.7％）

Ib（26.1％）and Ⅱa IM（28.3％）（P<0.05）.Expression rate of MG7-Ag

DNA aneuploid rate and percentage of S phase cell werestatistically higher in the type Ⅱb IM with dysphsia（62.5％

62.5％ and 143±32）than in typeⅡb 1M without dysplasia（47.3％

12.5％and12.7±2.9）（P<0.05 and P<0.01）.These findingssuppor the supposed progressive process:CAG→type Ⅱb IM→dysplasia→GC

andtype Ⅱb IM with dysplasia is closely associated with GC.

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