Effects of Chinese patent medicine Niaoduqing on adenineinduced chronic renal failure in rats

邓虹珠; 石兴华; 陈志良; 丁彦青; 陈业豪

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Effects of Chinese patent medicine Niaoduqing on adenineinduced chronic renal failure in rats

Updated：2026-03-12

- Effects of Chinese patent medicine Niaoduqing on adenineinduced chronic renal failure in rats
- Effects of Chinese patent medicine Niaoduqing on adenineinduced chronic renal failure in rats
- 解放军医学杂志（英文版） 1993年第4期页码：400-405
- Affiliations：
  
  1. Pharmaceutical Department Nan fang Hospital
  2. First Military Medical University
  3. ,Guangzhou,510515
  4. Department of Pathology
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：1993
- Accepted：
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Effects of Chinese patent medicine Niaoduqing on adenineinduced chronic renal failure in rats[J]. 解放军医学杂志（英文版）, 1993,(4):400-405.

[1]邓虹珠,石兴华,陈志良,丁彦青,陈业豪.Effects of Chinese patent medicine Niaoduqing on adenineinduced chronic renal failure in rats[J].Journal of Medical Colleges of PLA,1993(04):400-405.
Effects of Chinese patent medicine Niaoduqing on adenineinduced chronic renal failure in rats[J]. 解放军医学杂志（英文版）, 1993,(4):400-405. DOI：

[1]邓虹珠,石兴华,陈志良,丁彦青,陈业豪.Effects of Chinese patent medicine Niaoduqing on adenineinduced chronic renal failure in rats[J].Journal of Medical Colleges of PLA,1993(04):400-405. DOI：

摘要

Abstract

<正> The authors made rat model of chronic renal failure by feeding the animals with foodcontaining 0.5 % adenine and treated with Niaoduqing（NDQ）

a Chinese patent medicine

whichcomposed of Rhizoma Rhei

Radix Glycyrrhizae

Radix Paeoniae Alba

etc.The rats were divid-ed into four groups:model control

normal control;and two NDQ-treated groups with high andlow doses separately.The blood tests including urea nitrogen（BUN）

serum creatinine（Scr）

red blood cell（RBC）

hemoglobin （Hb） hematocrit （HCT）

sodium （Na）

potassium （K）

cal-cium（Ca）and phosphate（P）levels were performed atthe fourth week and the eighth week

thetime of sacrifice.The results showed that in the NDQ-treated groups the mean levels of BUN andScr were lower and the mean values of RBC

Hb and HCT

higher than those in the untreatedcontrol group.In the NDQ-treated groups

hyperphosphatemia and hypocalcemia of rats im-proved

the deposited crystals of adenine metabolite and the proliferation of fibroid tissue in kid-ney decreased.These findings indicate that NDQ can ameliorate the symptoms of chronic renalfailure and delay the progress of this disease.

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