Effects of thromboxane and prostacyclin imbalance on hemodynamics and hemorrheology in severely burn patients

黄跃生; 杨宗诚; 黎鳌

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Effects of thromboxane and prostacyclin imbalance on hemodynamics and hemorrheology in severely burn patients

Updated：2026-03-12

- Effects of thromboxane and prostacyclin imbalance on hemodynamics and hemorrheology in severely burn patients
- Effects of thromboxane and prostacyclin imbalance on hemodynamics and hemorrheology in severely burn patients
- 解放军医学杂志（英文版） 1991年第4期页码：299-303
- Affiliations：
  
  1. Research Institute of Bum Medicine Southwest Hospital
  2. Third Military Medical College
  3. ,Chongqing,630038
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：1991
- Accepted：
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Effects of thromboxane and prostacyclin imbalance on hemodynamics and hemorrheology in severely burn patients[J]. 解放军医学杂志（英文版）, 1991,(4):299-303.

[1]黄跃生,杨宗诚,黎鳌.Effects of thromboxane and prostacyclin imbalance on hemodynamics and hemorrheology in severely burn patients[J].Journal of Medical Colleges of PLA,1991(04):299-303.
Effects of thromboxane and prostacyclin imbalance on hemodynamics and hemorrheology in severely burn patients[J]. 解放军医学杂志（英文版）, 1991,(4):299-303. DOI：

[1]黄跃生,杨宗诚,黎鳌.Effects of thromboxane and prostacyclin imbalance on hemodynamics and hemorrheology in severely burn patients[J].Journal of Medical Colleges of PLA,1991(04):299-303. DOI：

摘要

Abstract

正

Fifty-seven bum patients were dosdy observed for 28 d postburn.In general

plasma levelof thromboxane B

（TXB

）

6-keto-PGF

and TXB

/6-keto-PGF

ratio all rose up abruptly tothe peak in the first half day after burns and then declined gradually.However the patterns of theirchanges were different:6-keto-PGF

returned to the control level in the 2nd day postburn

remained in a higher level than the control even in the 5th day postburn

and the increase ofTXB

/6-keto-PGF

lα

ratio was especially pronounced in the first 3 d postbum.It was also shownthat the changes of hemodynamics and hemorrheology occurred simultaneously with the imbalanceof thromboxane and prcstacyclin in the early postburn stage.The extent of the imbalance accordedwith the severity of hemodynamical and hemorrheological changes and was closely correlated withthe changes with the stroke volume

cardiac output

systemic vascular resistance

circulatory plateletaggregate ratio

platelet count and blood vinery.These findings suggest that the imbalance be-tween thromboxane and prostacyclin plays an important role in the changes of hemodynamics andhemorrheology in severe burn cases.

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