Effects of electric field stimulation on endogenous enkephalin content in artery wall
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Effects of electric field stimulation on endogenous enkephalin content in artery wall
Effects of electric field stimulation on endogenous enkephalin content in artery wall
解放军医学杂志(英文版)1991年第4期 页码:304-308
Affiliations:
1. Department of Physiology Fourth Military Medical University
2. ,Xi’an,710032
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纸质出版:1991
Accepted:
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Effects of electric field stimulation on endogenous enkephalin content in artery wall[J]. 解放军医学杂志(英文版), 1991,(4):304-308.
[1]林树新,范瑾之,刘琨,王复周.Effects of electric field stimulation on endogenous enkephalin content in artery wall[J].Journal of Medical Colleges of PLA,1991(04):304-308.
Effects of electric field stimulation on endogenous enkephalin content in artery wall[J]. 解放军医学杂志(英文版), 1991,(4):304-308.DOI:
[1]林树新,范瑾之,刘琨,王复周.Effects of electric field stimulation on endogenous enkephalin content in artery wall[J].Journal of Medical Colleges of PLA,1991(04):304-308.DOI:
Effects of electric field stimulation on endogenous enkephalin content in artery wall
摘要
Abstract
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After 20min electric field stimulation
L-enkephalin (L-ENK) content in the rabbitear artery declined from the control value of 38.99±17.29 to 12.55±1.96pg/mg of wet tissue(n=12)
and M-enkephalin (M-ENK) content from 134.67±8.11 to 73.68±17.96pg/mg of wet tis-sue (n=6)
both being significantly decreased.This effect was not influenced after blockade ofadrenergic receptor by yohimbine.Contractions of artery strips induced by electric field stimulationwere enhanced distinctly after pretreatment of the artery strips with naloxone
an opioid receptorblocker
and with pronase
but not after pretreatment with trypsin.The results suggested that the re-lease of endogenous enkephalins in the ear artery could be induced by electric field stimulation andx
2
-receptor might not participate in the release course
The release amount of ENK from the ar-terv strips increased when the stimulus freduency increased within the range of 2 Hz to 8 Hz.
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