Stereological study of quantitative relationships between morphological and functional changes of the lungs in early phase of blast injury in rats

赵敏; 王正国; 刘大维; 王声文

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Stereological study of quantitative relationships between morphological and functional changes of the lungs in early phase of blast injury in rats

Updated：2026-03-12

- Stereological study of quantitative relationships between morphological and functional changes of the lungs in early phase of blast injury in rats
- Stereological study of quantitative relationships between morphological and functional changes of the lungs in early phase of blast injury in rats
- 解放军医学杂志（英文版） 1992年第1期页码：41-44
- Affiliations：
  
  1. Research Institute of Surgery Third Military Medical College
  2. ,Chongqing,630042
- Author bio：
- Funds：
  
  This study was supported by the National Natural Sciences Foundation of China
- DOI：
  中图分类号：
- 纸质出版：1992
- Accepted：
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Stereological study of quantitative relationships between morphological and functional changes of the lungs in early phase of blast injury in rats[J]. 解放军医学杂志（英文版）, 1992,(1):41-44.

[1]赵敏,王正国,刘大维,王声文.Stereological study of quantitative relationships between morphological and functional changes of the lungs in early phase of blast injury in rats[J].Journal of Medical Colleges of PLA,1992(01):41-44+48.
Stereological study of quantitative relationships between morphological and functional changes of the lungs in early phase of blast injury in rats[J]. 解放军医学杂志（英文版）, 1992,(1):41-44. DOI：

[1]赵敏,王正国,刘大维,王声文.Stereological study of quantitative relationships between morphological and functional changes of the lungs in early phase of blast injury in rats[J].Journal of Medical Colleges of PLA,1992(01):41-44+48. DOI：

摘要

Abstract

正

The morphological and functional changes of the lungs in the early phase of blast injurywere analyzed and related quantitatively in rats with microcomputer-assisted morphometry.It wasfound that（1）significant or partial correlation exists between stereological and functional indices

（2）changes of the endothelium and epithelium rather than the interstitium contribute to the increase ofharmonic and arithmetic thickness(T

)of the air-blood barrier

and（3）the regression equa-tions are as follows:（a）PaO

=3.56+1.62DL（O

）

r=0.678

P=0.032:（b）PaO

=2.99+3.49DL（O

）-0.0005S

+0.003S

-38.2V

-0.257T

-0.028Dt（O

）

=0.9999

P=0.008;（c）PaCO

=7.69+0.0001S

-4.35T

+19.7T

-46.2T

-4.4T

aen

-5.87T

aep

=0.9999

P=0.014;（d）pH=3.068+0.0005S

-1.79T

+12.2T

-50.8T

-2.52T

aint

+0.69DL（O

）

=0.9999

P=0.10.The significance and application of stereology in theestablishment of the quantitative relationship between morphological and functional indices are dis-cussed.Mathematical models to relate morphometric parameters to functional changes are possible.

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