Double potentialities of tumoricide and hematopoiesis of human bone marrow cells activated by IL-2 and IL-3

郭坤元; 黄平; 冯永清; 陆志刚; 王小宁; 王军; 汪森明; 沈淑华

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Double potentialities of tumoricide and hematopoiesis of human bone marrow cells activated by IL-2 and IL-3

Updated：2026-03-12

- Double potentialities of tumoricide and hematopoiesis of human bone marrow cells activated by IL-2 and IL-3
- Double potentialities of tumoricide and hematopoiesis of human bone marrow cells activated by IL-2 and IL-3
- 解放军医学杂志（英文版） 1993年第2期页码：162-168
- Affiliations：
  
  1. Department of Oncology Zhujiang Hospital
  2. First Military Medical University
  3. ,Guangzhou,510282
- Author bio：
- Funds：
- DOI：
  中图分类号：
- 纸质出版：1993
- Accepted：
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Double potentialities of tumoricide and hematopoiesis of human bone marrow cells activated by IL-2 and IL-3[J]. 解放军医学杂志（英文版）, 1993,(2):162-168.

[1]郭坤元,黄平,冯永清,陆志刚,王小宁,王军,汪森明,沈淑华.Double potentialities of tumoricide and hematopoiesis of human bone marrow cells activated by IL-2 and IL-3[J].Journal of Medical Colleges of PLA,1993(02):162-168.
Double potentialities of tumoricide and hematopoiesis of human bone marrow cells activated by IL-2 and IL-3[J]. 解放军医学杂志（英文版）, 1993,(2):162-168. DOI：

[1]郭坤元,黄平,冯永清,陆志刚,王小宁,王军,汪森明,沈淑华.Double potentialities of tumoricide and hematopoiesis of human bone marrow cells activated by IL-2 and IL-3[J].Journal of Medical Colleges of PLA,1993(02):162-168. DOI：

摘要

Abstract

<正> The biomodulative and hematopoietic potentialities of IL-2 and IL-3 activatedbone marrow（ABM）cells from patients with lung adenocarcinoma were studied in vitro.Human bone marrow（BM）cells could be activated by IL-2 in culture for 7d.TheseIL-2 ABM cells had higher cytolytic activities against cells of H 7402 cell line and freshautologous adenocarcinoma cells and maintained the cytotoxicities longer than IL-2 acti-vated peripheral blood lymphocytes（APBLs）

a point of possible importance in adoptiveimmunotherapy for cancer patients.The IL-2 ABM cells also had similar number ofBFU-E and CFU-GM to that had fresh BM cells if 1L-3 was added 48h alter IL-2 inculture.The IL-2 and IL-3 ABM cells might be used to eliminate tumor cells and tosupply reconstitutive elements of BM for autologous bone marrow transplantation.

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