Increased serum and ascitic fluid levels of soluble tumor necrosis factor-p55 in hepatocellular carcinoma patients

高蕾; 白岚; 南清振; 杨希山; 陈凯; 温汉平; 柏林; 张亚历; 张振书

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Increased serum and ascitic fluid levels of soluble tumor necrosis factor-p55 in hepatocellular carcinoma patients

Updated：2026-03-12

- Increased serum and ascitic fluid levels of soluble tumor necrosis factor-p55 in hepatocellular carcinoma patients
- Increased serum and ascitic fluid levels of soluble tumor necrosis factor-p55 in hepatocellular carcinoma patients
- 解放军医学杂志（英文版） 2002年第3期页码：232-234
- Affiliations：
  
  1. Department of Oncology
  2. Hospital of Chinese PLA,157
  3. ,Guangzhou,510515
  4. Institute of Digestive Diseases of Chinese PLA
  5. Nanfang Hospital
  6. First Military Medical University
- Author bio：
- Funds：
- DOI：
  中图分类号： R735.7
- 纸质出版：2002
- Accepted：
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Increased serum and ascitic fluid levels of soluble tumor necrosis factor-p55 in hepatocellular carcinoma patients[J]. 解放军医学杂志（英文版）, 2002,(3):232-234.

[1]高蕾,白岚,南清振,杨希山,陈凯,温汉平,柏林,张亚历,张振书.Increased serum and ascitic fluid levels of soluble tumor necrosis factor-p55 in hepatocellular carcinoma patients[J].Journal of Medical Colleges of PLA,2002(03):232-234.
Increased serum and ascitic fluid levels of soluble tumor necrosis factor-p55 in hepatocellular carcinoma patients[J]. 解放军医学杂志（英文版）, 2002,(3):232-234. DOI：

[1]高蕾,白岚,南清振,杨希山,陈凯,温汉平,柏林,张亚历,张振书.Increased serum and ascitic fluid levels of soluble tumor necrosis factor-p55 in hepatocellular carcinoma patients[J].Journal of Medical Colleges of PLA,2002(03):232-234. DOI：

摘要

Abstract

<正> Objective: To explore the levels of serum and ascitic fluid soluble tumor necrosis factor receptor-p55 （sTNFR-p55） and understand their clinical implication in primary hepatocellular carcinoma （HCC） patients. Methods: Enzyme-linked immunosorbent assay （ELISA） was used to examine the levels of sTNFR-p55 in the serum and ascitic fluid in 25 HCC patients and 25 patients with liver cirrhosis （LC）. The test was also performed on the serum of 30 healthy subjects who served as control group. To assess the clinical effects of increased serum concentrations of sTNFR-p55

four parameters were analyzed by logistic regression. Results: Serum and ascitic fluid levels of sTNFR-p55 in HCC patients were significantly higher than those in LC patients and controls （P=0. 001）. No significant difference was found between serum sTNFR-p55 levels in the latter 2 groups （P = 0. 19）

and positive correlation between serum levels of sTNFR-p55 and that in ascitic fluid was noted in the 2 patient groups （r=1. 000

P<0. 001）. Level

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