Relationship between heterogeneity of HBV preS/S gene and intrauter-ine transmission

李端; 闫永平; 徐德忠; 张景霞

Your Location：

Home >

Browse articles >

Relationship between heterogeneity of HBV preS/S gene and intrauter-ine transmission

Updated：2026-03-12

- Relationship between heterogeneity of HBV preS/S gene and intrauter-ine transmission
- Relationship between heterogeneity of HBV preS/S gene and intrauter-ine transmission
- 解放军医学杂志（英文版） 2002年第2期页码：112-115
- Affiliations：
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China （No. 39970652）
- DOI：
  中图分类号： R714.251
- 纸质出版：2002
- Accepted：
Scan QR Code
Relationship between heterogeneity of HBV preS/S gene and intrauter-ine transmission[J]. 解放军医学杂志（英文版）, 2002,(2):112-115.

[1]李端,,,,,,,,,,闫永平,,,,,,,,,,徐德忠,,,,,,,,,,张景霞.Relationship between heterogeneity of HBV preS/S gene and intrauter-ine transmission[J].Journal of Medical Colleges of PLA,2002(02):112-115.
Relationship between heterogeneity of HBV preS/S gene and intrauter-ine transmission[J]. 解放军医学杂志（英文版）, 2002,(2):112-115. DOI：

[1]李端,,,,,,,,,,闫永平,,,,,,,,,,徐德忠,,,,,,,,,,张景霞.Relationship between heterogeneity of HBV preS/S gene and intrauter-ine transmission[J].Journal of Medical Colleges of PLA,2002(02):112-115. DOI：

摘要

Abstract

<正>Objective: To study the relationship of the mutation of HBV preS/S gene in HBsAg carrying pregnant women and intrauterine transmission. Methods: Polymerase chain reaction （PCR） was used to amplify HBV preS/S gene from sera of 8 HBsAg carrying pregnant women

4 women’s neonates infected with HBV

and the other’s neonates non-infected with. The PCR products were cloned and 5 clones were chosen from every woman for DNA sequencing. Results: Heterogeneity of HBV preS/S gene in HBsAg carrying pregnant women having intrauterine transmission was much higher than that from having not intrauterine transmission

and the divergence rate of nucleotide sequences also higher strikingly. Conclusion: High heterogeneity of HBV preS/S gene of HBsAg positive pregnant women may be relative to high rate of intrauterine transmis-

关键词

Keywords

references

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

暂无数据