Effects of quercetin on hepatocyte stimulating factor production by mouse peritoneal macrophages

周斌; 张俊平; 刘宏; 殷明; 钱定华

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Effects of quercetin on hepatocyte stimulating factor production by mouse peritoneal macrophages

Updated：2026-03-12

- Effects of quercetin on hepatocyte stimulating factor production by mouse peritoneal macrophages
- Effects of quercetin on hepatocyte stimulating factor production by mouse peritoneal macrophages
- 解放军医学杂志（英文版） 2003年第2期页码：121-123
- Affiliations：
  
  1. Department of Pharmacology
  2. School of Pharmacy
- Author bio：
- Funds：
  
  Supported by the National Natural Science Foundation of China（No.39370798,30200344）
- DOI：
  中图分类号： R965
- 纸质出版：2003
- Accepted：
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Effects of quercetin on hepatocyte stimulating factor production by mouse peritoneal macrophages[J]. 解放军医学杂志（英文版）, 2003,(2):121-123.

[1]周斌,张俊平,刘宏,殷明,钱定华.Effects of quercetin on hepatocyte stimulating factor production by mouse peritoneal macrophages[J].Journal of Medical Colleges of PLA,2003(02):121-123.
Effects of quercetin on hepatocyte stimulating factor production by mouse peritoneal macrophages[J]. 解放军医学杂志（英文版）, 2003,(2):121-123. DOI：

[1]周斌,张俊平,刘宏,殷明,钱定华.Effects of quercetin on hepatocyte stimulating factor production by mouse peritoneal macrophages[J].Journal of Medical Colleges of PLA,2003(02):121-123. DOI：

摘要

Abstract

<正> Objective: To study the effects of quercetin on hepatocyte stimulating factor production from mouse perito-neal macrophages. Methods: Hepatocyte stimulating factor was evaluated by the amount of fibrinogen synthesized inHep3B cells. Interleukin-6 activity was measured by B9 cell proliferation methyl thiazolyl tetrazolium colorimetric meth-od. Hep3B cell supernatant fibrinogen was quantitated with ELISA. Results: LPS induced the synthesis of hepatocytestimulating factor in mouse peritoneal macrophages

and hepatocyte stimulating factor promotes the synthesis of fibrino-gen from Hep3B cells. Quercetin（5 to 40 μmol/L） inhibited the synthesis of hepatocyte stimulating factor stimulated

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