Experiment study of Swainsonine’s antineoplastic activity

王四旺; 李予蓉; 孙纪元; 谢艳华

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Experiment study of Swainsonine’s antineoplastic activity

Updated：2026-03-12

- Experiment study of Swainsonine’s antineoplastic activity
- Experiment study of Swainsonine’s antineoplastic activity
- 解放军医学杂志（英文版） 2003年第3期页码：191
- Affiliations：
  
  1. Institute of Materia Medica
  2. Administration of Scientific Research
  3. Department of Radiation Medicine
  4. School of Preventive Medicine
  5. Fourth Military Medical University
  6. ,China
- Author bio：
- Funds：
- DOI：
  中图分类号： R965
- 纸质出版：2003
- Accepted：
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Experiment study of Swainsonine’s antineoplastic activity[J]. 解放军医学杂志（英文版）, 2003,(3):191.

[1]王四旺,李予蓉,孙纪元,谢艳华.Experiment study of Swainsonine's antineoplastic activity[J].Journal of Medical Colleges of PLA,2003(03):191.
Experiment study of Swainsonine’s antineoplastic activity[J]. 解放军医学杂志（英文版）, 2003,(3):191. DOI：

[1]王四旺,李予蓉,孙纪元,谢艳华.Experiment study of Swainsonine's antineoplastic activity[J].Journal of Medical Colleges of PLA,2003(03):191. DOI：

摘要

Abstract

正

of Pure Swainsonine （SW） to EMT6 cell strain is 1.2（0.8-1.6）mg/L and the dose of entire lethalis 6.4 mg/L with MTT method. After ig crude extraction of SW to S

180

sareoma rooted in mouse and EMT

model micewith breast carcinoma for 12 d at dose of 16 mg/kg

the inhibitory rates of weight amounts to 49.7% and 49.4% re-spectively （P

0.01）.Given crude extraction of SW at 4 mg/kg combined with irradiation at 5 Gy

Co-γ

the inhibi-tory rate of weight of S

180

amount to 64.5% （P

0.01）.It shows that SW has obviously antineoplastic.

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