Elevated plasma level of matrix metalloproteinases-9 and its significance in patients with abdominal aortic aneurysms

马中; Joerg.HECKENKAMP; Jan.BRUNKWALL; 陈江浩; 陈美芬

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Elevated plasma level of matrix metalloproteinases-9 and its significance in patients with abdominal aortic aneurysms

Updated：2026-03-12

- Elevated plasma level of matrix metalloproteinases-9 and its significance in patients with abdominal aortic aneurysms
- Elevated plasma level of matrix metalloproteinases-9 and its significance in patients with abdominal aortic aneurysms
- 解放军医学杂志（英文版） 2003年第5期页码：305-307
- Affiliations：
  
  1. Department of Vascular Surgery
  2. Xijing Hospital
  3. Fourth Military Medical University
  4. ,Germany
  5. Vascular Surgery Center
  6. Colonge University Hospital
  7. Colonge,50924
- Author bio：
- Funds：
- DOI：
  中图分类号： R654.3
- 纸质出版：2003
- Accepted：
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Elevated plasma level of matrix metalloproteinases-9 and its significance in patients with abdominal aortic aneurysms[J]. 解放军医学杂志（英文版）, 2003,(5):305-307.

[1]马中,Joerg.HECKENKAMP,Jan.BRUNKWALL,陈江浩,陈美芬.Elevated plasma level of matrix metalloproteinases-9 and its significance in patients with abdominal aortic aneurysms[J].Journal of Medical Colleges of PLA,2003(05):305-307.
Elevated plasma level of matrix metalloproteinases-9 and its significance in patients with abdominal aortic aneurysms[J]. 解放军医学杂志（英文版）, 2003,(5):305-307. DOI：

[1]马中,Joerg.HECKENKAMP,Jan.BRUNKWALL,陈江浩,陈美芬.Elevated plasma level of matrix metalloproteinases-9 and its significance in patients with abdominal aortic aneurysms[J].Journal of Medical Colleges of PLA,2003(05):305-307. DOI：

摘要

Abstract

<正> Objective: To investigate the changes of the plasma level of MMP-9 （ Matrix Metalloproteinase-9

MMP-9） in the patients with abdominal aortic aneurysms （ AAAs） before and after the treatment

and evaluate the significance of MMP-9 in the pathogenesis of AAAs. Methods: Blood samples of 35 patients with AAAs and 10 patients with the arterial occlusive diseases （ AODs）

which enrolled into the Vascular Surgery Center of Colonge University Hospital from February to August of 2002

were collected before and one month after surgical repair or less-invasive endovascu-lar exclusion. The plasma concentrations of MMP-9 of all the collected samples were measured by means of enzyme-linked immunosorbent assay （ ELISA）

and compared between the two groups patients at different time point. Results: The mean plasma concentration of MMP-9 of AAAs was significantly higher than that of AODs prior to treatment [（90.3±9.1） ng/ml vs （23. 6±7. 3） ng/ml

P < 0. 05 ]

and no apparent difference was showed in the patients w

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