<正>Objective: To study the effects of hyperbaric air exposure on the functions of peritoneal macrophages of mice. Methods: Forty-eight mice were equally randomized to 6 groups: （1） normal air group （NA）; （2） hyperbaric air group 1 （HA1）; （3） hyperbaric air group 2 （HA2）; （4） hyperbaric air group 3 （HA3）; （5） hyperbaric oxygen group （HO）;（6） hyperbaric nitrogen group （HN）. Every group was exposed to corresponding pressure for 60 min

twice a day for 3 d. Peritoneal macrophages were obtained at the corresponding time to observe the changes of phagocytosis

acid phos-phatase

antigen presentation function and the produce of NO and TNF-α. Results: Compared with those in NA group

the activity of phagocytosis

acid phosphatase

antigen presentation function and the produce of NO and TNF-a were markedly inhibited in hyperbaric oxygen group and hyperbaric air group 1 （ P < 0.05

P < 0.01） and they changed little in HN group. These changes could disappear in 3 - 5 d. Conclusion: The functions of mice peritoneal ma