In vitro toxicologic study of chitin short fiber reinforced polycaprolactone composite

段亮; 徐志飞; 秦雄; 孙康; 赵学维; 方嘉; 龚志云

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In vitro toxicologic study of chitin short fiber reinforced polycaprolactone composite

Updated：2026-03-12

- In vitro toxicologic study of chitin short fiber reinforced polycaprolactone composite
- In vitro toxicologic study of chitin short fiber reinforced polycaprolactone composite
- 解放军医学杂志（英文版） 2004年第6期页码：353-356
- Affiliations：
  
  1. Department of Cardiothoracic Surgery
  2. Changzheng Hospital
  3. Second Military Medical University
  4. ,Shanghai,200030
  5. Institute of Composite Materials
  6. Shanghai Jiaotong University
- Author bio：
- Funds：
  
  Supported by the Sci & Tech Development Foundation of Shang-hai （No. 024419076）
- DOI：
  中图分类号： R99
- 纸质出版：2004
- Accepted：
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In vitro toxicologic study of chitin short fiber reinforced polycaprolactone composite[J]. 解放军医学杂志（英文版）, 2004,(6):353-356.

[1]段亮,徐志飞,秦雄,孙康,赵学维,方嘉,龚志云.In vitro toxicologic study of chitin short fiber reinforced polycaprolactone composite[J].Journal of Medical Colleges of PLA,2004(06):353-356.
In vitro toxicologic study of chitin short fiber reinforced polycaprolactone composite[J]. 解放军医学杂志（英文版）, 2004,(6):353-356. DOI：

[1]段亮,徐志飞,秦雄,孙康,赵学维,方嘉,龚志云.In vitro toxicologic study of chitin short fiber reinforced polycaprolactone composite[J].Journal of Medical Colleges of PLA,2004(06):353-356. DOI：

摘要

Abstract

<正>Objective: To investigate the cytotoxicity and cytocompatibility of chitin fiber reinforced polycaprolactone composite in vitro in order to provide useful scientific basis for clinical application. Methods: Cell morphology observation

MTT and DNA assay were used to evaluate the influence of the composite on the morphology

growth and proliferation of cultured L-929 cells. Results: The composite did not impair the morphology of cultured cells in vitro. MTT and DNA assay demonstrated that the growth and proliferation of the cultured cells were not significantly inhibited by the composite. Conclusion : The composites have fine cytocompatibility and are safe for clinical use of reconstruction of chest wall defects.

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