The influence of ultraviolet blood irradiation and oxygenation on oxygen free radicals metabolism in rabbits with soman intoxication

张献清; 张晓迪; 穆士杰; 陈蕤; 夏爱军; 梁欣; 海春旭

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The influence of ultraviolet blood irradiation and oxygenation on oxygen free radicals metabolism in rabbits with soman intoxication

Updated：2026-03-12

- The influence of ultraviolet blood irradiation and oxygenation on oxygen free radicals metabolism in rabbits with soman intoxication
- The influence of ultraviolet blood irradiation and oxygenation on oxygen free radicals metabolism in rabbits with soman intoxication
- 解放军医学杂志（英文版） 2006年第1期页码：42-44
- Affiliations：
  
  1. Department of Blood TransfusionXijing Hospital Fourth Military Medical University
  2. ,China
  3. Department of ToxicologyFourth Military Medical University
- Author bio：
- Funds：
- DOI：
  中图分类号： R82
- 纸质出版：2006
- Accepted：
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The influence of ultraviolet blood irradiation and oxygenation on oxygen free radicals metabolism in rabbits with soman intoxication[J]. 解放军医学杂志（英文版）, 2006,(1):42-44.

[1]张献清,张晓迪,穆士杰,陈蕤,夏爱军,梁欣,海春旭.The influence of ultraviolet blood irradiation and oxygenation on oxygen free radicals metabolism in rabbits with soman intoxication[J].Journal of Medical Colleges of PLA,2006(01):42-44.
The influence of ultraviolet blood irradiation and oxygenation on oxygen free radicals metabolism in rabbits with soman intoxication[J]. 解放军医学杂志（英文版）, 2006,(1):42-44. DOI：

[1]张献清,张晓迪,穆士杰,陈蕤,夏爱军,梁欣,海春旭.The influence of ultraviolet blood irradiation and oxygenation on oxygen free radicals metabolism in rabbits with soman intoxication[J].Journal of Medical Colleges of PLA,2006(01):42-44. DOI：

摘要

Abstract

<正>Objective: To investigate the effect of ultraviolet blood irradiation and oxygenation （UBIO） on the metabolism of oxygen free radicals in rabbits with acute soman intoxication. Methods: One hundred rabbits were randomly divided into 5 groups: normal control group

intoxication group

routine therapy group. UBIO therapy group and combined therapy group. After 14 d

the concentration of malondiadehyde（MDA） and activity of superoxide dismutase（SOD）

glutathionperoxidase（GSH-Px）

catalase （CAT） and total antioxidative capacity （T-AOC） in serum were determined respectively. Results: Compared with the normal control group

the concentration of MDA and activity of CAT in the intoxication group were significantly higher （P < 0. 05）. but SOD. GSH-Px activity and T-AOC were significantly lower （P<0. 05）. After UBIO or combined therapy

serum MDA level was significantly lower in comparison with intoxication group （P<0. 05）. but the activity of SOD. GSH-Px

CAT and T-AOC were higher than intoxication group（P<0. 05）. Conclusion: There is an obvious oxygen free radical injury in rabbits with a-cute soman intoxication. UBIO can improve the antioxidation ability of rabbits and may be applied to treat acute soman intoxication as adjunctive therapy.

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