<正>Objective:To retrospectively compare the efficacy and safety of ultrasound-guided thrombin injection （UGTI） with ultrasound-guided compression repair （UGCR） in patients with postcatheter-izational femoral arterial pseudoaneurysms （PSA）. Methods: Thirty patients of this iatrogenic PSA [8 males

22 females

average age （66. 5±5. 2） years] in our institution from 1997 to 2004 were retrospectively analyzed. Among them

11 patients were treated with UGCR

2 under continuous ultrasonographic （US） guidance and 9 under the guidance of femoral arterial bruit auscultation and dorsalis pedis artery palpation. Because UGCR was failed in 5 patients

consecutively 24 patients were treated with UGTI. Swine thrombin solution at a concentration of 200 U/ml was injected percutaneously using 22-25 gauge needles under color Doppler US. Demographics

clinical variables

pseudoaneurysm characteristics

and results of the 2 groups were compared by using Fisher’s exact test and Student’s t test. Results: The initial success rate of UGCR was 36. 4% （4/11） and the overall success rate was 45. 5% （5/11）. Ten of 11 patients suffered from local pain during the compression

but there was no any complication in UGTI group. The average dose of injected thrombin was （180 + 82） U for PSA of a single loculus and （315±150） U for multiloculated PSA. The initial success rate of UGTI was 89.5% （17/19） and the overall success rate was 100% （24/24）. Conclusion;UGTI offers a safe

quick and effective means of definitively treating femoral pseudoaneurysms and seems superior to UGCR. The amount of thrombin applied on our people seems smaller compared with others’ work.