<正>Objective:To explore the serum levels of resistin and adiponectin in patients with overweight and obesity.Methods:Fifty-eight cases with normal weight and 24 patients with overweight and obesity have taken fasting blood samples for measurements of plasma glucose

plasma lipids

insulin

C-peptide

thyroid hormones

C-response protein

interleukin-6

TNF-α

leptin

adiponectin and resistin.Results: The concentrations of resistin in cases with overweight and obesity were significant higher than those in the normal weight cases （16.01±8.60 vs 11.63±9.05ng/ml

P=0.047）.Pearson relation analysis showed that serum resistin concentrations were positively correlated with age （r=0.476

P=0.019）

but negatively correlated with C-peptide （r=-0.45

P=0.024）

and adiponectin concentrations were posi- tively correlated with HDL-c （r=0.463

P=0.023） and systolic blood pressure （r=0.409

P=0.047）in overweight and obesity cases.Conclusion:The concentrations of resistin in cases with over-weight and obesity are higher

and there is no correlation between resistin and blood glucose

blood lipids and insulin

while the serum adiponectin concentrations positively correlated with HDL-c and systolic blood pressure.