Treatment of intractable chronic pelvic pain syndrome by injecting a compound of Bupivacaine and Fentanyl into sacral spinal space

周占松; 宋波; 聂发传; 陈金梅

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Treatment of intractable chronic pelvic pain syndrome by injecting a compound of Bupivacaine and Fentanyl into sacral spinal space

Updated：2026-03-12

- Treatment of intractable chronic pelvic pain syndrome by injecting a compound of Bupivacaine and Fentanyl into sacral spinal space
- Treatment of intractable chronic pelvic pain syndrome by injecting a compound of Bupivacaine and Fentanyl into sacral spinal space
- 解放军医学杂志（英文版） 2006年第4期页码：258-260
- Affiliations：
  
  1. Uronary Surgery Research Center Southwest Hospital
  2. Third Military Medical University
  3. ,China
  4. Department of Anesthesiology
- Author bio：
- Funds：
- DOI：
  中图分类号： R681.6
- 纸质出版：2006
- Accepted：
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Treatment of intractable chronic pelvic pain syndrome by injecting a compound of Bupivacaine and Fentanyl into sacral spinal space[J]. 解放军医学杂志（英文版）, 2006,(4):258-260.

[1]周占松,宋波,聂发传,陈金梅.Treatment of intractable chronic pelvic pain syndrome by injecting a compound of Bupivacaine and Fentanyl into sacral spinal space[J].Journal of Medical Colleges of PLA,2006(04):258-260.
Treatment of intractable chronic pelvic pain syndrome by injecting a compound of Bupivacaine and Fentanyl into sacral spinal space[J]. 解放军医学杂志（英文版）, 2006,(4):258-260. DOI：

[1]周占松,宋波,聂发传,陈金梅.Treatment of intractable chronic pelvic pain syndrome by injecting a compound of Bupivacaine and Fentanyl into sacral spinal space[J].Journal of Medical Colleges of PLA,2006(04):258-260. DOI：

摘要

Abstract

<正>Objective:To investigate the effect of injecting a compound of Bupivacaine and Fentanyl into sacral spinal space to treat chronic pelvic pain syndrome （CPPS）. Methods: A total of 36 men with recalcitrant CPPS refractory to multiple prior therapies were treated with the injection of a compound of Bupivacaine and Fentanyl （10 ml of 0. 125% Bupivacaine

0. 05 mg Fentanyl

5 mg Dexamethasone

100 mg Vitamin B1 and 1 mg Vitamin B12） into sacral space once a week for 4 weeks. The National Institute of Health Chronic Proslatitis Symptom Index （NIH-CPSI）

maximum and average flow rate were performed at the start and the end of 4 weeks’ therapy. Results :Mean NIH-CPSI total score was decreased from 26. 5±1. 6 to 13. 4±2. 0 （P<0. 001）. Significant improvement was seen in each subscore domain. A total of 32 patients （89%） had at least 25% improvement on NIH-CPSI and 22 （61 %） had at least 50% improvement. Maximal and average flow rate were increased from 19. 5±3. 8 to 23. 6±4. 2 and 10. 9±2. 6 to 14. 3±2. 4 respectively. Conclusion: Injection of this compound of Bupivacaine

Fentanyl and Dexamethasone into sacral spinal space is an effective and safe approach for recalcitrant CPPS. Further study of the mechanisms and prospective placebo controlled trials are warranted.

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